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  1. Proper binocular vision depends on the routing at the optic chiasm of the correct proportion of retinal ganglion cell (RGC) axons that project to the same (ipsilateral) and opposite (contralateral) side of the...

    Authors: Punita Bhansali, Ilana Rayport, Alexandra Rebsam and Carol Mason
    Citation: Neural Development 2014 9:11
    Content type: Research article Published on:

  3. Morphogenesis of the zebrafish neural tube requires the coordinated movement of many cells in both time and space. A good example of this is the movement of the cells in the zebrafish neural plate as they conv...

    Authors: Claudio Araya, Marcel Tawk, Gemma C Girdler, Marta Costa, Carlos Carmona-Fontaine and Jonathan DW Clarke
    Citation: Neural Development 2014 9:9
    Content type: Research article Published on:

  4. As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b. The shared presence of four specific amino acid motifs—M1 to M4—in the N-terminal region of mamm...

    Authors: Alejandro Pinzón-Olejua, Cornelia Welte, Houari Abdesselem, Edward Málaga-Trillo and Claudia AO Stuermer
    Citation: Neural Development 2014 9:8
    Content type: Research article Published on:

  5. Latrophilins (LPHNs) are a small family of neuronal adhesion-GPCRs originally discovered as receptors for the black widow spider toxin α-latrotoxin. Mutations in LPHN3 have recently been identified as risk factor...

    Authors: Matthew L O’Sullivan, Francesca Martini, Sventja von Daake, Davide Comoletti and Anirvan Ghosh
    Citation: Neural Development 2014 9:7
    Content type: Research article Published on:

  6. The genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poor...

    Authors: Matthew J Eckler, Kathryn A Larkin, William L McKenna, Sol Katzman, Chao Guo, Robin Roque, Axel Visel, John L L Rubenstein and Bin Chen
    Citation: Neural Development 2014 9:6
    Content type: Research article Published on:

  7. Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is req...

    Authors: Biliana O Veleva-Rotse, James L Smart, Annette F Baas, Benjamin Edmonds, Zi-ming Zhao, Allyson Brown, Lillian R Klug, Kelly Hansen, Gabrielle Reilly, Alexandria P Gardner, Krishnaveni Subbiah, Eric A Gaucher, Hans Clevers and Anthony P Barnes
    Citation: Neural Development 2014 9:5
    Content type: Research article Published on:

  8. Vertebrates and invertebrates obtain visual motion information by channeling moving visual cues perceived by the retina through specific motion sensitive synaptic relays in the brain. In Drosophila, the series of...

    Authors: Carlos Oliva, Ching-Man Choi, Laura J J Nicolai, Natalia Mora, Natalie De Geest and Bassem A Hassan
    Citation: Neural Development 2014 9:4
    Content type: Research article Published on:

  10. There are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene. This functional specificity is derived from distinct RGC ...

    Authors: Jason W Triplett, Wei Wei, Cristina Gonzalez, Neal T Sweeney, Andrew D Huberman, Marla B Feller and David A Feldheim
    Citation: Neural Development 2014 9:2
    Content type: Research article Published on:

  11. The functional integration of the cerebellum into a number of different neural systems is governed by the connection of its output axons. In amniotes, the majority of this output is mediated by an evolutionari...

    Authors: Mary J Green and Richard JT Wingate
    Citation: Neural Development 2014 9:1
    Content type: Research article Published on:

  12. The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. It is well known ...

    Authors: Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé
    Citation: Neural Development 2013 8:25
    Content type: Research article Published on:

  13. The dorsal lateral geniculate nucleus (dLGN) of the mouse thalamus has emerged as a powerful experimental system for understanding the refinement of developing sensory connections. Interestingly, many of the b...

    Authors: Tania A Seabrook, Thomas E Krahe, Gubbi Govindaiah and William Guido
    Citation: Neural Development 2013 8:24
    Content type: Short Report Published on:

  14. During the EMBO course ‘Imaging of Neural Development in Zebrafish’, held on September 9–15th 2013, researchers from different backgrounds shared their latest results, ideas and practical expertise on zebrafish a...

    Authors: Steffen Scholpp, Lucia Poggi and Mihaela Žigman
    Citation: Neural Development 2013 8:23
    Content type: Meeting report Published on:

  15. Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution assays have established that the XMAP215/Dis1/TOG family of MT regulators function as MT ‘plus-e...

    Authors: Laura Anne Lowery, Alina Stout, Anna E Faris, Liya Ding, Michelle A Baird, Michael W Davidson, Gaudenz Danuser and David Van Vactor
    Citation: Neural Development 2013 8:22
    Content type: Research article Published on:

  17. Hearing depends on correct functioning of the cochlear hair cells, and their innervation by spiral ganglion neurons. Most of the insight into the embryological and molecular development of this sensory system ...

    Authors: Heiko Locher, Johan HM Frijns, Liesbeth van Iperen, John CMJ de Groot, Margriet A Huisman and Susana M Chuva de Sousa Lopes
    Citation: Neural Development 2013 8:20
    Content type: Research Article Published on:

  18. The conserved habenular neural circuit relays cognitive information from the forebrain into the ventral mid- and hindbrain. In zebrafish, the bilaterally formed habenulae in the dorsal diencephalon are made up...

    Authors: Carlo A Beretta, Nicolas Dross, Peter Bankhead and Matthias Carl
    Citation: Neural Development 2013 8:19
    Content type: Research Article Published on:

  19. Circuit formation in the nervous system essentially relies on the proper development of neurons and their processes. In this context, the ubiquitin ligase Nedd4 is a crucial modulator of axonal and dendritic b...

    Authors: Michael J Schmeisser, Susanne J Kühl, Michael Schoen, Nathalie H Beth, Tobias M Weis, Andreas M Grabrucker, Michael Kühl and Tobias M Boeckers
    Citation: Neural Development 2013 8:18
    Content type: Research Article Published on:

  21. Neurons in sympathetic ganglia and neuroendocrine cells in the adrenal medulla share not only their embryonic origin from sympathoadrenal precursors in the neural crest but also a range of functional features....

    Authors: Jutta Stubbusch, Priyanka Narasimhan, Katrin Huber, Klaus Unsicker, Hermann Rohrer and Uwe Ernsberger
    Citation: Neural Development 2013 8:16
    Content type: Research Article Published on:

  22. Spinal commissural axons represent a model system for deciphering the molecular logic that regulates the guidance of midline-crossing axons in the developing central nervous system (CNS). Whether the same or s...

    Authors: Tracy S Tran, Edward Carlin, Ruihe Lin, Edward Martinez, Jane E Johnson and Zaven Kaprielian
    Citation: Neural Development 2013 8:15
    Content type: Research article Published on:

  23. During cerebral cortex development, multipotent neural progenitor cells generate a variety of neuronal subtypes in a fixed temporal order. How a single neural progenitor cell generates the diversity of cortica...

    Authors: Nathalie Saurat, Therese Andersson, Navneet A Vasistha, Zoltan Molnar and Frederick J Livesey
    Citation: Neural Development 2013 8:14
    Content type: Research article Published on:

  24. In order to fulfill their chemosensory function, olfactory neurons are in direct contact with the external environment and are therefore exposed to environmental aggressive factors. Olfaction is maintained thr...

    Authors: Marie Paschaki, Laura Cammas, Yuko Muta, Yoko Matsuoka, Siu-Shan Mak, Monika Rataj-Baniowska, Valurie Fraulob, Pascal Dolle and Raj K Ladher
    Citation: Neural Development 2013 8:13
    Content type: Research article Published on:

  25. The neural crest (NC) is a transient embryonic structure unique to vertebrates, which generates peripheral sensory and autonomic neurons, glia, neuroendocrine chromaffin and thyroid C-cells, melanocytes, and m...

    Authors: Stella Shtukmaster, Marie Catherine Schier, Katrin Huber, Shlomo Krispin, Chaya Kalcheim and Klaus Unsicker
    Citation: Neural Development 2013 8:12
    Content type: Research article Published on:

  27. The conserved Caenorhabditis elegans proteins NID-1/nidogen and PTP-3A/LAR-RPTP function to efficiently localize the presynaptic scaffold protein SYD-2/α-liprin at active zones. Loss of function in these molecule...

    Authors: Raymond C Caylor, Yishi Jin and Brian D Ackley
    Citation: Neural Development 2013 8:10
    Content type: Research article Published on:

  28. Teleost fish display widespread post-embryonic neurogenesis originating from many different proliferative niches that are distributed along the brain axis. During the development of the central nervous system ...

    Authors: Jan Kaslin, Volker Kroehne, Francesca Benato, Francesco Argenton and Michael Brand
    Citation: Neural Development 2013 8:9
    Content type: Research article Published on:

  30. During cerebral cortical development, neural precursor-precursor interactions in the ventricular zone neurogenic niche coordinate signaling pathways that regulate proliferation and differentiation. Previous st...

    Authors: Jianing Zhang, Julie R Shemezis, Erin R McQuinn, Jing Wang, Maria Sverdlov and Anjen Chenn
    Citation: Neural Development 2013 8:7
    Content type: Research article Published on:

  31. The central complex is a multimodal information-processing center in the insect brain composed of thousands of neurons representing more than 50 neural types arranged in a stereotyped modular neuroarchitecture...

    Authors: Nadia Riebli, Gudrun Viktorin and Heinrich Reichert
    Citation: Neural Development 2013 8:6
    Content type: Research article Published on:

  32. Morphogenesis requires developmental processes to occur both at the right time and in the right place. During neural tube formation in the zebrafish embryo, the generation of the apical specializations of the ...

    Authors: Gemma C Girdler, Claudio Araya, Xiaoyun Ren and Jonathan DW Clarke
    Citation: Neural Development 2013 8:5
    Content type: Research article Published on:

  33. During rat development, histamine (HA) is one of the first neuroactive molecules to appear in the brain, reaching its maximal value at embryonic day 14, a period when neurogenesis of deep layers is occurring i...

    Authors: Anayansi Molina-Hernández, Griselda Rodríguez-Martínez, Itzel Escobedo-Ávila and Iván Velasco
    Citation: Neural Development 2013 8:4
    Content type: Research article Published on:

  34. Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as intern...

    Authors: Rebecca Schmidt, Uwe Strähle and Steffen Scholpp
    Citation: Neural Development 2013 8:3
    Content type: Review Published on:

  35. Studies of developmental plasticity may provide insight into plasticity during adulthood, when neural circuitry is less responsive to losses or changes in input. In the mammalian auditory brainstem, globular b...

    Authors: Paul A Nakamura and Karina S Cramer
    Citation: Neural Development 2013 8:2
    Content type: Research article Published on:

  37. The homeobox containing transcription factor Uncx4.1 is, amongst others, expressed in the mouse midbrain. The early expression of this transcription factor in the mouse, as well as in the chick midbrain, point...

    Authors: Tamara I Rabe, Gundula Griesel, Stephen Blanke, Andreas Kispert, Michael Leitges, Bert van der Zwaag, J Peter H Burbach, Frédérique Varoqueaux and Ahmed Mansouri
    Citation: Neural Development 2012 7:39
    Content type: Research article Published on:

  38. During development, excess synapses form between the central and peripheral nervous systems that are then eliminated to achieve correct connectivity. In the peripheral auditory system, the developing type I sp...

    Authors: Lin-Chien Huang, Meagan Barclay, Kevin Lee, Saša Peter, Gary D Housley, Peter R Thorne and Johanna M Montgomery
    Citation: Neural Development 2012 7:38
    Content type: Research article Published on:

  39. Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination. Signal transduction appears to be mediat...

    Authors: Melissa M Langworthy and Bruce Appel
    Citation: Neural Development 2012 7:37
    Content type: Research article Published on:

  40. Axons navigate to their future synaptic targets with the help of choice points, intermediate targets that express axon guidance cues. Once they reach a choice point, axons need to switch their response from at...

    Authors: Melanie Philipp, Vera Niederkofler, Marc Debrunner, Tobias Alther, Beat Kunz and Esther T Stoeckli
    Citation: Neural Development 2012 7:36
    Content type: Research article Published on:

  41. Precise matching between motoneuron subtypes and the muscles they innervate is a prerequisite for normal behavior. Motoneuron subtype identity is specified by the combination of transcription factors expressed...

    Authors: Steve D Seredick, Liesl Van Ryswyk, Sarah A Hutchinson and Judith S Eisen
    Citation: Neural Development 2012 7:35
    Content type: Research article Published on:

  42. Drosophila neurons have dendrites that contain minus-end-out microtubules. This microtubule arrangement is different from that of cultured mammalian neurons, which have mixed polarity microtubules in dendrites.

    Authors: Sarah E Hill, Manpreet Parmar, Kyle W Gheres, Michelle A Guignet, Yanmei Huang, F Rob Jackson and Melissa M Rolls
    Citation: Neural Development 2012 7:34
    Content type: Research article Published on:

  43. Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique midkine gene in mammals has two paralogs in zebrafish: midkine-a (mdka) and midkine-b (mdkb). In the z...

    Authors: Jing Luo, Rosa A Uribe, Sarah Hayton, Anda-Alexandra Calinescu, Jeffrey M Gross and Peter F Hitchcock
    Citation: Neural Development 2012 7:33
    Content type: Research article Published on:

  44. Although the mechanisms underlying brain patterning and regionalization are very much conserved, the morphology of different brain regions is extraordinarily variable across vertebrate phylogeny. This is espec...

    Authors: Mónica Folgueira, Philippa Bayley, Pavla Navratilova, Thomas S Becker, Stephen W Wilson and Jonathan DW Clarke
    Citation: Neural Development 2012 7:212
    Content type: Research article Published on:

    The Erratum to this article has been published in Neural Development 2015 10:22

  45. In holometabolous insects such as Drosophila melanogaster, neuroblasts produce an initial population of diverse neurons during embryogenesis and a much larger set of adult-specific neurons during larval life. In ...

    Authors: Elizabeth C Marin, Katie E Dry, Danielle R Alaimo, Kirstin T Rudd, Anthony R Cillo, Michael E Clenshaw, Nicolas Negre, Kevin P White and James W Truman
    Citation: Neural Development 2012 7:31
    Content type: Research article Published on:

  46. The zebrafish retina maintains two populations of stem cells: first, the germinal zone or ciliary marginal zone (CMZ) contains multipotent retinal progenitors that add cells to the retinal periphery as the fis...

    Authors: Jason R Meyers, Lily Hu, Ariel Moses, Kavon Kaboli, Annemarie Papandrea and Pamela A Raymond
    Citation: Neural Development 2012 7:30
    Content type: Research article Published on:

  49. Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regene...

    Authors: Caghan Kizil, Stefanie Dudczig, Nikos Kyritsis, Anja Machate, Juliane Blaesche, Volker Kroehne and Michael Brand
    Citation: Neural Development 2012 7:27
    Content type: Research article Published on:

  50. Recent findings have indicated the presence of a progenitor domain at the marginal zone/layer 1 of the cerebral cortex, and it has been suggested that these progenitors have neurogenic and gliogenic potential....

    Authors: Joshua J Breunig, David Gate, Rachelle Levy, Javier Rodriguez Jr, Gi Bum Kim, Moise Danielpour, Clive N Svendsen and Terrence Town
    Citation: Neural Development 2012 7:26
    Content type: Methodology Published on:

Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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Neural Development

ISSN: 1749-8104