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  1. The functional integration of the cerebellum into a number of different neural systems is governed by the connection of its output axons. In amniotes, the majority of this output is mediated by an evolutionari...

    Authors: Mary J Green and Richard JT Wingate

    Citation: Neural Development 2014 9:1

    Content type: Research article

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  2. The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. It is well known ...

    Authors: Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé

    Citation: Neural Development 2013 8:25

    Content type: Research article

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  3. The dorsal lateral geniculate nucleus (dLGN) of the mouse thalamus has emerged as a powerful experimental system for understanding the refinement of developing sensory connections. Interestingly, many of the b...

    Authors: Tania A Seabrook, Thomas E Krahe, Gubbi Govindaiah and William Guido

    Citation: Neural Development 2013 8:24

    Content type: Short Report

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  4. During the EMBO course ‘Imaging of Neural Development in Zebrafish’, held on September 9–15th 2013, researchers from different backgrounds shared their latest results, ideas and practical expertise on zebrafish a...

    Authors: Steffen Scholpp, Lucia Poggi and Mihaela Žigman

    Citation: Neural Development 2013 8:23

    Content type: Meeting report

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  5. Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution assays have established that the XMAP215/Dis1/TOG family of MT regulators function as MT ‘plus-e...

    Authors: Laura Anne Lowery, Alina Stout, Anna E Faris, Liya Ding, Michelle A Baird, Michael W Davidson, Gaudenz Danuser and David Van Vactor

    Citation: Neural Development 2013 8:22

    Content type: Research article

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  7. Hearing depends on correct functioning of the cochlear hair cells, and their innervation by spiral ganglion neurons. Most of the insight into the embryological and molecular development of this sensory system ...

    Authors: Heiko Locher, Johan HM Frijns, Liesbeth van Iperen, John CMJ de Groot, Margriet A Huisman and Susana M Chuva de Sousa Lopes

    Citation: Neural Development 2013 8:20

    Content type: Research Article

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  8. The conserved habenular neural circuit relays cognitive information from the forebrain into the ventral mid- and hindbrain. In zebrafish, the bilaterally formed habenulae in the dorsal diencephalon are made up...

    Authors: Carlo A Beretta, Nicolas Dross, Peter Bankhead and Matthias Carl

    Citation: Neural Development 2013 8:19

    Content type: Research Article

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  9. Circuit formation in the nervous system essentially relies on the proper development of neurons and their processes. In this context, the ubiquitin ligase Nedd4 is a crucial modulator of axonal and dendritic b...

    Authors: Michael J Schmeisser, Susanne J Kühl, Michael Schoen, Nathalie H Beth, Tobias M Weis, Andreas M Grabrucker, Michael Kühl and Tobias M Boeckers

    Citation: Neural Development 2013 8:18

    Content type: Research Article

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  11. Neurons in sympathetic ganglia and neuroendocrine cells in the adrenal medulla share not only their embryonic origin from sympathoadrenal precursors in the neural crest but also a range of functional features....

    Authors: Jutta Stubbusch, Priyanka Narasimhan, Katrin Huber, Klaus Unsicker, Hermann Rohrer and Uwe Ernsberger

    Citation: Neural Development 2013 8:16

    Content type: Research Article

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  12. Spinal commissural axons represent a model system for deciphering the molecular logic that regulates the guidance of midline-crossing axons in the developing central nervous system (CNS). Whether the same or s...

    Authors: Tracy S Tran, Edward Carlin, Ruihe Lin, Edward Martinez, Jane E Johnson and Zaven Kaprielian

    Citation: Neural Development 2013 8:15

    Content type: Research article

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  13. During cerebral cortex development, multipotent neural progenitor cells generate a variety of neuronal subtypes in a fixed temporal order. How a single neural progenitor cell generates the diversity of cortica...

    Authors: Nathalie Saurat, Therese Andersson, Navneet A Vasistha, Zoltan Molnar and Frederick J Livesey

    Citation: Neural Development 2013 8:14

    Content type: Research article

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  14. In order to fulfill their chemosensory function, olfactory neurons are in direct contact with the external environment and are therefore exposed to environmental aggressive factors. Olfaction is maintained thr...

    Authors: Marie Paschaki, Laura Cammas, Yuko Muta, Yoko Matsuoka, Siu-Shan Mak, Monika Rataj-Baniowska, Valurie Fraulob, Pascal Dolle and Raj K Ladher

    Citation: Neural Development 2013 8:13

    Content type: Research article

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  15. The neural crest (NC) is a transient embryonic structure unique to vertebrates, which generates peripheral sensory and autonomic neurons, glia, neuroendocrine chromaffin and thyroid C-cells, melanocytes, and m...

    Authors: Stella Shtukmaster, Marie Catherine Schier, Katrin Huber, Shlomo Krispin, Chaya Kalcheim and Klaus Unsicker

    Citation: Neural Development 2013 8:12

    Content type: Research article

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  17. The conserved Caenorhabditis elegans proteins NID-1/nidogen and PTP-3A/LAR-RPTP function to efficiently localize the presynaptic scaffold protein SYD-2/α-liprin at active zones. Loss of function in these molecule...

    Authors: Raymond C Caylor, Yishi Jin and Brian D Ackley

    Citation: Neural Development 2013 8:10

    Content type: Research article

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  18. Teleost fish display widespread post-embryonic neurogenesis originating from many different proliferative niches that are distributed along the brain axis. During the development of the central nervous system ...

    Authors: Jan Kaslin, Volker Kroehne, Francesca Benato, Francesco Argenton and Michael Brand

    Citation: Neural Development 2013 8:9

    Content type: Research article

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  20. During cerebral cortical development, neural precursor-precursor interactions in the ventricular zone neurogenic niche coordinate signaling pathways that regulate proliferation and differentiation. Previous st...

    Authors: Jianing Zhang, Julie R Shemezis, Erin R McQuinn, Jing Wang, Maria Sverdlov and Anjen Chenn

    Citation: Neural Development 2013 8:7

    Content type: Research article

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  21. The central complex is a multimodal information-processing center in the insect brain composed of thousands of neurons representing more than 50 neural types arranged in a stereotyped modular neuroarchitecture...

    Authors: Nadia Riebli, Gudrun Viktorin and Heinrich Reichert

    Citation: Neural Development 2013 8:6

    Content type: Research article

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  22. Morphogenesis requires developmental processes to occur both at the right time and in the right place. During neural tube formation in the zebrafish embryo, the generation of the apical specializations of the ...

    Authors: Gemma C Girdler, Claudio Araya, Xiaoyun Ren and Jonathan DW Clarke

    Citation: Neural Development 2013 8:5

    Content type: Research article

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  23. During rat development, histamine (HA) is one of the first neuroactive molecules to appear in the brain, reaching its maximal value at embryonic day 14, a period when neurogenesis of deep layers is occurring i...

    Authors: Anayansi Molina-Hernández, Griselda Rodríguez-Martínez, Itzel Escobedo-Ávila and Iván Velasco

    Citation: Neural Development 2013 8:4

    Content type: Research article

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  24. Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as intern...

    Authors: Rebecca Schmidt, Uwe Strähle and Steffen Scholpp

    Citation: Neural Development 2013 8:3

    Content type: Review

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  25. Studies of developmental plasticity may provide insight into plasticity during adulthood, when neural circuitry is less responsive to losses or changes in input. In the mammalian auditory brainstem, globular b...

    Authors: Paul A Nakamura and Karina S Cramer

    Citation: Neural Development 2013 8:2

    Content type: Research article

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  27. The homeobox containing transcription factor Uncx4.1 is, amongst others, expressed in the mouse midbrain. The early expression of this transcription factor in the mouse, as well as in the chick midbrain, point...

    Authors: Tamara I Rabe, Gundula Griesel, Stephen Blanke, Andreas Kispert, Michael Leitges, Bert van der Zwaag, J Peter H Burbach, Frédérique Varoqueaux and Ahmed Mansouri

    Citation: Neural Development 2012 7:39

    Content type: Research article

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  28. During development, excess synapses form between the central and peripheral nervous systems that are then eliminated to achieve correct connectivity. In the peripheral auditory system, the developing type I sp...

    Authors: Lin-Chien Huang, Meagan Barclay, Kevin Lee, Saša Peter, Gary D Housley, Peter R Thorne and Johanna M Montgomery

    Citation: Neural Development 2012 7:38

    Content type: Research article

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  29. Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination. Signal transduction appears to be mediat...

    Authors: Melissa M Langworthy and Bruce Appel

    Citation: Neural Development 2012 7:37

    Content type: Research article

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  30. Axons navigate to their future synaptic targets with the help of choice points, intermediate targets that express axon guidance cues. Once they reach a choice point, axons need to switch their response from at...

    Authors: Melanie Philipp, Vera Niederkofler, Marc Debrunner, Tobias Alther, Beat Kunz and Esther T Stoeckli

    Citation: Neural Development 2012 7:36

    Content type: Research article

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  31. Precise matching between motoneuron subtypes and the muscles they innervate is a prerequisite for normal behavior. Motoneuron subtype identity is specified by the combination of transcription factors expressed...

    Authors: Steve D Seredick, Liesl Van Ryswyk, Sarah A Hutchinson and Judith S Eisen

    Citation: Neural Development 2012 7:35

    Content type: Research article

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  32. Drosophila neurons have dendrites that contain minus-end-out microtubules. This microtubule arrangement is different from that of cultured mammalian neurons, which have mixed polarity microtubules in dendrites.

    Authors: Sarah E Hill, Manpreet Parmar, Kyle W Gheres, Michelle A Guignet, Yanmei Huang, F Rob Jackson and Melissa M Rolls

    Citation: Neural Development 2012 7:34

    Content type: Research article

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  33. Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique midkine gene in mammals has two paralogs in zebrafish: midkine-a (mdka) and midkine-b (mdkb). In the z...

    Authors: Jing Luo, Rosa A Uribe, Sarah Hayton, Anda-Alexandra Calinescu, Jeffrey M Gross and Peter F Hitchcock

    Citation: Neural Development 2012 7:33

    Content type: Research article

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  34. Although the mechanisms underlying brain patterning and regionalization are very much conserved, the morphology of different brain regions is extraordinarily variable across vertebrate phylogeny. This is espec...

    Authors: Mónica Folgueira, Philippa Bayley, Pavla Navratilova, Thomas S Becker, Stephen W Wilson and Jonathan DW Clarke

    Citation: Neural Development 2012 7:212

    Content type: Research article

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    The Erratum to this article has been published in Neural Development 2015 10:22

  35. In holometabolous insects such as Drosophila melanogaster, neuroblasts produce an initial population of diverse neurons during embryogenesis and a much larger set of adult-specific neurons during larval life. In ...

    Authors: Elizabeth C Marin, Katie E Dry, Danielle R Alaimo, Kirstin T Rudd, Anthony R Cillo, Michael E Clenshaw, Nicolas Negre, Kevin P White and James W Truman

    Citation: Neural Development 2012 7:31

    Content type: Research article

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  36. The zebrafish retina maintains two populations of stem cells: first, the germinal zone or ciliary marginal zone (CMZ) contains multipotent retinal progenitors that add cells to the retinal periphery as the fis...

    Authors: Jason R Meyers, Lily Hu, Ariel Moses, Kavon Kaboli, Annemarie Papandrea and Pamela A Raymond

    Citation: Neural Development 2012 7:30

    Content type: Research article

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  39. Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regene...

    Authors: Caghan Kizil, Stefanie Dudczig, Nikos Kyritsis, Anja Machate, Juliane Blaesche, Volker Kroehne and Michael Brand

    Citation: Neural Development 2012 7:27

    Content type: Research article

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  40. Recent findings have indicated the presence of a progenitor domain at the marginal zone/layer 1 of the cerebral cortex, and it has been suggested that these progenitors have neurogenic and gliogenic potential....

    Authors: Joshua J Breunig, David Gate, Rachelle Levy, Javier Rodriguez Jr, Gi Bum Kim, Moise Danielpour, Clive N Svendsen and Terrence Town

    Citation: Neural Development 2012 7:26

    Content type: Methodology

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  41. The secreted ligand Reelin is believed to regulate the translocation of prospective layer 6 (L6) neocortical neurons into the preplate, a loose layer of pioneer neurons that overlies the ventricular zone. Rece...

    Authors: Ryan S O’Dell, Candida J M Ustine, David A Cameron, Sean M Lawless, Rebecca M Williams, Warren R Zipfel and Eric C Olson

    Citation: Neural Development 2012 7:25

    Content type: Research article

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  42. Pannexin 1 forms ion and metabolite permeable hexameric channels and is abundantly expressed in the brain. After discovering pannexin 1 expression in postnatal neural stem and progenitor cells we sought to elu...

    Authors: Leigh E Wicki-Stordeur, Adrian D Dzugalo, Rose M Swansburg, Jocelyne M Suits and Leigh Anne Swayne

    Citation: Neural Development 2012 7:11

    Content type: Research article

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  43. The pre B-cell leukemia transcription factor 1 (Pbx1) genes belong to the three amino acid loop extension family of homeodomain proteins that form hetero-oligomeric complexes with other homeodomain transcription ...

    Authors: Paola Sgadò, Elisabetta Ferretti, Daniel Grbec, Yuri Bozzi and Horst H Simon

    Citation: Neural Development 2012 7:24

    Content type: Research article

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  44. The sensory neurons and glia of the dorsal root ganglia (DRG) arise from neural crest cells in the developing vertebrate embryo. In mouse and chick, DRG formation is completed during embryogenesis. In contrast...

    Authors: Hillary Faye McGraw, Corey D Snelson, Andrew Prendergast, Arminda Suli and David W Raible

    Citation: Neural Development 2012 7:23

    Content type: Research article

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  46. During neocortical development, multiple voltage- and ligand-gated ion channels are differentially expressed in neurons thereby shaping their intrinsic electrical properties. One of these voltage-gated ion cha...

    Authors: Arne Battefeld, Nino Rocha, Konstantin Stadler, Anja U Bräuer and Ulf Strauss

    Citation: Neural Development 2012 7:21

    Content type: Research article

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  47. Sulfated glycosaminoglycan chains are known for their regulatory functions during neural development and regeneration. However, it is still unknown whether the sulfate residues alone influence, for example, ne...

    Authors: Michael Karus, Samira Samtleben, Claudia Busse, Teresa Tsai, Irmgard D Dietzel, Andreas Faissner and Stefan Wiese

    Citation: Neural Development 2012 7:20

    Content type: Research Article

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  48. Understanding the cellular mechanisms regulating axon degeneration and regeneration is crucial for developing treatments for nerve injury and neurodegenerative disease. In neurons, axon degeneration is distinc...

    Authors: Rosario Villegas, Seanna M Martin, Kelley C O’Donnell, Simon A Carrillo, Alvaro Sagasti and Miguel L Allende

    Citation: Neural Development 2012 7:19

    Content type: Research article

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  49. Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While midline crossing is achieved through coordinated signaling of attractive and repulsiv...

    Authors: Jennifer Bonner, Michael Letko, Oliver Brant Nikolaus, Lisa Krug, Alexandria Cooper, Benjamin Chadwick, Phoebe Conklin, Amy Lim, Chi-Bin Chien and Richard I Dorsky

    Citation: Neural Development 2012 7:18

    Content type: Research Article

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Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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Neural Development

ISSN: 1749-8104