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  1. Content type: Review

    Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as intern...

    Authors: Rebecca Schmidt, Uwe Strähle and Steffen Scholpp

    Citation: Neural Development 2013 8:3

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  2. Content type: Research article

    Studies of developmental plasticity may provide insight into plasticity during adulthood, when neural circuitry is less responsive to losses or changes in input. In the mammalian auditory brainstem, globular b...

    Authors: Paul A Nakamura and Karina S Cramer

    Citation: Neural Development 2013 8:2

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  4. Content type: Research article

    The homeobox containing transcription factor Uncx4.1 is, amongst others, expressed in the mouse midbrain. The early expression of this transcription factor in the mouse, as well as in the chick midbrain, point...

    Authors: Tamara I Rabe, Gundula Griesel, Stephen Blanke, Andreas Kispert, Michael Leitges, Bert van der Zwaag, J Peter H Burbach, Frédérique Varoqueaux and Ahmed Mansouri

    Citation: Neural Development 2012 7:39

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  5. Content type: Research article

    During development, excess synapses form between the central and peripheral nervous systems that are then eliminated to achieve correct connectivity. In the peripheral auditory system, the developing type I sp...

    Authors: Lin-Chien Huang, Meagan Barclay, Kevin Lee, Saša Peter, Gary D Housley, Peter R Thorne and Johanna M Montgomery

    Citation: Neural Development 2012 7:38

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  6. Content type: Research article

    Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination. Signal transduction appears to be mediat...

    Authors: Melissa M Langworthy and Bruce Appel

    Citation: Neural Development 2012 7:37

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  7. Content type: Research article

    Axons navigate to their future synaptic targets with the help of choice points, intermediate targets that express axon guidance cues. Once they reach a choice point, axons need to switch their response from at...

    Authors: Melanie Philipp, Vera Niederkofler, Marc Debrunner, Tobias Alther, Beat Kunz and Esther T Stoeckli

    Citation: Neural Development 2012 7:36

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  8. Content type: Research article

    Precise matching between motoneuron subtypes and the muscles they innervate is a prerequisite for normal behavior. Motoneuron subtype identity is specified by the combination of transcription factors expressed...

    Authors: Steve D Seredick, Liesl Van Ryswyk, Sarah A Hutchinson and Judith S Eisen

    Citation: Neural Development 2012 7:35

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  9. Content type: Research article

    Drosophila neurons have dendrites that contain minus-end-out microtubules. This microtubule arrangement is different from that of cultured mammalian neurons, which have mixed polarity microtubules in dendrites.

    Authors: Sarah E Hill, Manpreet Parmar, Kyle W Gheres, Michelle A Guignet, Yanmei Huang, F Rob Jackson and Melissa M Rolls

    Citation: Neural Development 2012 7:34

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  10. Content type: Research article

    Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique midkine gene in mammals has two paralogs in zebrafish: midkine-a (mdka) and midkine-b (mdkb). In the z...

    Authors: Jing Luo, Rosa A Uribe, Sarah Hayton, Anda-Alexandra Calinescu, Jeffrey M Gross and Peter F Hitchcock

    Citation: Neural Development 2012 7:33

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  11. Content type: Research article

    Although the mechanisms underlying brain patterning and regionalization are very much conserved, the morphology of different brain regions is extraordinarily variable across vertebrate phylogeny. This is espec...

    Authors: Mónica Folgueira, Philippa Bayley, Pavla Navratilova, Thomas S Becker, Stephen W Wilson and Jonathan DW Clarke

    Citation: Neural Development 2012 7:212

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    The Erratum to this article has been published in Neural Development 2015 10:22

  12. Content type: Research article

    In holometabolous insects such as Drosophila melanogaster, neuroblasts produce an initial population of diverse neurons during embryogenesis and a much larger set of adult-specific neurons during larval life. In ...

    Authors: Elizabeth C Marin, Katie E Dry, Danielle R Alaimo, Kirstin T Rudd, Anthony R Cillo, Michael E Clenshaw, Nicolas Negre, Kevin P White and James W Truman

    Citation: Neural Development 2012 7:31

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  13. Content type: Research article

    The zebrafish retina maintains two populations of stem cells: first, the germinal zone or ciliary marginal zone (CMZ) contains multipotent retinal progenitors that add cells to the retinal periphery as the fis...

    Authors: Jason R Meyers, Lily Hu, Ariel Moses, Kavon Kaboli, Annemarie Papandrea and Pamela A Raymond

    Citation: Neural Development 2012 7:30

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  16. Content type: Research article

    Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regene...

    Authors: Caghan Kizil, Stefanie Dudczig, Nikos Kyritsis, Anja Machate, Juliane Blaesche, Volker Kroehne and Michael Brand

    Citation: Neural Development 2012 7:27

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  17. Content type: Methodology

    Recent findings have indicated the presence of a progenitor domain at the marginal zone/layer 1 of the cerebral cortex, and it has been suggested that these progenitors have neurogenic and gliogenic potential....

    Authors: Joshua J Breunig, David Gate, Rachelle Levy, Javier Rodriguez Jr, Gi Bum Kim, Moise Danielpour, Clive N Svendsen and Terrence Town

    Citation: Neural Development 2012 7:26

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  18. Content type: Research article

    The secreted ligand Reelin is believed to regulate the translocation of prospective layer 6 (L6) neocortical neurons into the preplate, a loose layer of pioneer neurons that overlies the ventricular zone. Rece...

    Authors: Ryan S O’Dell, Candida J M Ustine, David A Cameron, Sean M Lawless, Rebecca M Williams, Warren R Zipfel and Eric C Olson

    Citation: Neural Development 2012 7:25

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  19. Content type: Research article

    Pannexin 1 forms ion and metabolite permeable hexameric channels and is abundantly expressed in the brain. After discovering pannexin 1 expression in postnatal neural stem and progenitor cells we sought to elu...

    Authors: Leigh E Wicki-Stordeur, Adrian D Dzugalo, Rose M Swansburg, Jocelyne M Suits and Leigh Anne Swayne

    Citation: Neural Development 2012 7:11

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  20. Content type: Research article

    The pre B-cell leukemia transcription factor 1 (Pbx1) genes belong to the three amino acid loop extension family of homeodomain proteins that form hetero-oligomeric complexes with other homeodomain transcription ...

    Authors: Paola Sgadò, Elisabetta Ferretti, Daniel Grbec, Yuri Bozzi and Horst H Simon

    Citation: Neural Development 2012 7:24

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  21. Content type: Research article

    The sensory neurons and glia of the dorsal root ganglia (DRG) arise from neural crest cells in the developing vertebrate embryo. In mouse and chick, DRG formation is completed during embryogenesis. In contrast...

    Authors: Hillary Faye McGraw, Corey D Snelson, Andrew Prendergast, Arminda Suli and David W Raible

    Citation: Neural Development 2012 7:23

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  23. Content type: Research article

    During neocortical development, multiple voltage- and ligand-gated ion channels are differentially expressed in neurons thereby shaping their intrinsic electrical properties. One of these voltage-gated ion cha...

    Authors: Arne Battefeld, Nino Rocha, Konstantin Stadler, Anja U Bräuer and Ulf Strauss

    Citation: Neural Development 2012 7:21

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  24. Content type: Research Article

    Sulfated glycosaminoglycan chains are known for their regulatory functions during neural development and regeneration. However, it is still unknown whether the sulfate residues alone influence, for example, ne...

    Authors: Michael Karus, Samira Samtleben, Claudia Busse, Teresa Tsai, Irmgard D Dietzel, Andreas Faissner and Stefan Wiese

    Citation: Neural Development 2012 7:20

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  25. Content type: Research article

    Understanding the cellular mechanisms regulating axon degeneration and regeneration is crucial for developing treatments for nerve injury and neurodegenerative disease. In neurons, axon degeneration is distinc...

    Authors: Rosario Villegas, Seanna M Martin, Kelley C O’Donnell, Simon A Carrillo, Alvaro Sagasti and Miguel L Allende

    Citation: Neural Development 2012 7:19

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  26. Content type: Research Article

    Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While midline crossing is achieved through coordinated signaling of attractive and repulsiv...

    Authors: Jennifer Bonner, Michael Letko, Oliver Brant Nikolaus, Lisa Krug, Alexandria Cooper, Benjamin Chadwick, Phoebe Conklin, Amy Lim, Chi-Bin Chien and Richard I Dorsky

    Citation: Neural Development 2012 7:18

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  27. Content type: Research Article

    The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant re...

    Authors: Thomas K Knott, Pasil A Madany, Ashley A Faden, Mei Xu, Jörg Strotmann, Timothy R Henion and Gerald A Schwarting

    Citation: Neural Development 2012 7:17

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  30. Content type: Methodology

    In Drosophila, most neurogenetic research is carried out in vivo. Mammalian research demonstrates that primary cell culture techniques provide a powerful model to address cell autonomous and non-autonomous proces...

    Authors: Manuela M Moraru, Boris Egger, Diarra B Bao and Simon G Sprecher

    Citation: Neural Development 2012 7:14

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  31. Content type: Research article

    In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus) can regenerate their spinal cord after injury. However, the cellular and molecular mechanis...

    Authors: Marcia Gaete, Rosana Muñoz, Natalia Sánchez, Ricardo Tampe, Mauricio Moreno, Esteban G Contreras, Dasfne Lee-Liu and Juan Larraín

    Citation: Neural Development 2012 7:13

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  32. Content type: Research article

    A fundamental requirement for development of diverse brain regions is the function of local organizers at morphological boundaries. These organizers are restricted groups of cells that secrete signaling molecu...

    Authors: Benjamin Mattes, Sabrina Weber, João Peres, Qing Chen, Gary Davidson, Corinne Houart and Steffen Scholpp

    Citation: Neural Development 2012 7:12

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  33. Content type: Research article

    Cortical GABAergic interneurons (INs) are generated in the medial ganglionic eminence (MGE) and migrate tangentially into cortex. Because most, if not all, migrating MGE-derived INs express the neuregulin (NRG...

    Authors: Hao Li, Shen-Ju Chou, Tadashi Hamasaki, Carlos G Perez-Garcia and Dennis DM O'Leary

    Citation: Neural Development 2012 7:10

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  34. Content type: Research article

    The assembly of neural circuits requires the concerted action of both genetically determined and activity-dependent mechanisms. Calcium-regulated transcription may link these processes, but the influence of sp...

    Authors: Scott A Wilke, Benjamin J Hall, Joseph K Antonios, Laura A DeNardo, Stefanie Otto, Bo Yuan, Fading Chen, Elissa M Robbins, Katie Tiglio, Megan E Williams, Zilong Qiu, Thomas Biederer and Anirvan Ghosh

    Citation: Neural Development 2012 7:9

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  36. Content type: Research article

    The sequestration of Muscleblind splicing regulators results in myotonic dystrophy. Previous work on Muscleblind has largely focused on its roles in muscle development and maintenance due to the skeletal and c...

    Authors: Kerri A Spilker, George J Wang, Madina S Tugizova and Kang Shen

    Citation: Neural Development 2012 7:7

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  37. Content type: Research article

    Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans in embryonic neural environments suggests that ma...

    Authors: Jessica CF Kwok, Ying-Lai Yuen, Wai-Kit Lau, Fu-Xing Zhang, James W Fawcett, Ying-Shing Chan and Daisy KY Shum

    Citation: Neural Development 2012 7:6

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  40. Content type: Research article

    The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death. Recently, novel neural stem cells that amplify neural proliferation thr...

    Authors: Yanrui Jiang and Heinrich Reichert

    Citation: Neural Development 2012 7:3

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  41. Content type: Research article

    Tangential migration presents the primary mode of migration of cortical interneurons translocating into the cerebral cortex from subpallial domains. This migration takes place in multiple streams with the most...

    Authors: Konstantinos Zarbalis, Youngshik Choe, Julie A Siegenthaler, Lori A Orosco and Samuel J Pleasure

    Citation: Neural Development 2012 7:2

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  42. Content type: Research article

    In the decapod crustacean brain, neurogenesis persists throughout the animal's life. After embryogenesis, the central olfactory pathway integrates newborn olfactory local and projection interneurons that repla...

    Authors: Silvia Sintoni, Jeanne L Benton, Barbara S Beltz, Bill S Hansson and Steffen Harzsch

    Citation: Neural Development 2012 7:1

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  43. Content type: Research article

    Various members of the family of BTB/POZ zinc-finger transcription factors influence patterns of dendritic branching. One such member, Broad, is notable because its BrZ3 isoform is widely expressed in Drosophila ...

    Authors: Janet A Scott, Darren W Williams and James W Truman

    Citation: Neural Development 2011 6:39

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  45. Content type: Research article

    The phylogenetically conserved transcription factor Lola is essential for many aspects of axon growth and guidance, synapse formation and neural circuit development in Drosophila. To date it has been difficult, h...

    Authors: Michael A Gates, Ramakrishnan Kannan and Edward Giniger

    Citation: Neural Development 2011 6:37

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  46. Content type: Research article

    Bone morphogenetic protein (BMP)7 evokes both inductive and axon orienting responses in dorsal interneurons (dI neurons) in the developing spinal cord. These events occur sequentially during the development of...

    Authors: Jeanette C Perron and Jane Dodd

    Citation: Neural Development 2011 6:36

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  47. Content type: Research article

    The size and cell number of each brain region are influenced by the organization and behavior of neural progenitor cells during embryonic development. Recent studies on developing neocortex have revealed the p...

    Authors: Lynn Wang, Krista K Bluske, Lauren K Dickel and Yasushi Nakagawa

    Citation: Neural Development 2011 6:35

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  48. Content type: Research article

    The dopaminergic (DA) neurons present in the central brain of the Drosophila larva are spatially arranged in stereotyped groups that define clusters of bilaterally symmetrical neurons. These clusters have been cl...

    Authors: Jorge Blanco, Rahul Pandey, Martin Wasser and Gerald Udolph

    Citation: Neural Development 2011 6:34

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  49. Content type: Research article

    The mechanisms that consolidate neural circuitry are a major focus of neuroscience. In the mammalian cochlea, the refinement of spiral ganglion neuron (SGN) innervation to the inner hair cells (by type I SGNs)...

    Authors: Meagan Barclay, Allen F Ryan and Gary D Housley

    Citation: Neural Development 2011 6:33

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Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Kang Shen
Stanford University, USA

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Neural Development

ISSN: 1749-8104