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  1. Neural circuits can spontaneously generate complex spatiotemporal firing patterns during development. This spontaneous activity is thought to help guide development of the nervous system. In this study, we had...

    Authors: Paul Charlesworth, Ellese Cotterill, Andrew Morton, Seth GN Grant and Stephen J Eglen
    Citation: Neural Development 2015 10:1
  2. Eye development in vertebrates relies on the critical regulation of SOX2 expression. Humans with mutations in SOX2 often suffer from eye defects including anophthalmia (no eye) and microphthalmia (small eye). In ...

    Authors: Whitney E Heavner, Cynthia L Andoniadou and Larysa H Pevny
    Citation: Neural Development 2014 9:27
  3. During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) ...

    Authors: Niraj Trivedi, Joseph S Ramahi, Mahmut Karakaya, Danielle Howell, Ryan A Kerekes and David J Solecki
    Citation: Neural Development 2014 9:26
  4. Spontaneous retinal activity (SRA) is important during eye-specific segregation within the dorsal lateral geniculate nucleus (dLGN), but the feature(s) of activity critical for retinogeniculate refinement are ...

    Authors: Colenso M Speer, Chao Sun, Lauren C Liets, Ben K Stafford, Barbara Chapman and Hwai-Jong Cheng
    Citation: Neural Development 2014 9:25
  5. Neural crest cells (NCCs) are a transient embryonic cell type that give rise to a wide spectrum of derivatives, including neurons and glia of the sensory and autonomic nervous system, melanocytes and connectiv...

    Authors: Rachael Lumb, Sophie Wiszniak, Samuela Kabbara, Michaela Scherer, Natasha Harvey and Quenten Schwarz
    Citation: Neural Development 2014 9:24
  6. Neural stem cell (NSC) differentiation is a complex multistep process that persists in specific regions of the postnatal forebrain and requires tight regulation throughout life. The transcriptional control of ...

    Authors: Bruno Fischer, Kasum Azim, Anahí Hurtado-Chong, Sandra Ramelli, María Fernández and Olivier Raineteau
    Citation: Neural Development 2014 9:23
  7. Peripheral nerve injuries can severely affect the way that animals perceive signals from the surrounding environment. While damage to peripheral axons generally has a better outcome than injuries to central ne...

    Authors: Maria Laura Ceci, Camila Mardones-Krsulovic, Mario Sánchez, Leonardo E Valdivia and Miguel L Allende
    Citation: Neural Development 2014 9:22
  8. Neurotrophin-4 (NT-4) and brain derived neurotrophic factor (BDNF) bind to the same receptor, Ntrk2/TrkB, but play distinct roles in the development of the rodent gustatory system. However, the mechanisms unde...

    Authors: Juraj Koudelka, Jacqueline M Horn, Chinnavuth Vatanashevanopakorn and Liliana Minichiello
    Citation: Neural Development 2014 9:21
  9. Longitudinal axons grow parallel to the embryonic midline to connect distant regions of the central nervous system. Previous studies suggested that repulsive midline signals guide pioneer longitudinal axons by...

    Authors: Minkyung Kim, W Todd Farmer, Brielle Bjorke, Samuel A McMahon, Pierre J Fabre, Frédéric Charron and Grant S Mastick
    Citation: Neural Development 2014 9:17
  10. Mouse visual thalamus has emerged as a powerful model for understanding the mechanisms underlying neural circuit formation and function. Three distinct nuclei within mouse thalamus receive retinal input, the d...

    Authors: Sarah Hammer, Gabriela L Carrillo, Gubbi Govindaiah, Aboozar Monavarfeshani, Joseph S Bircher, Jianmin Su, William Guido and Michael A Fox
    Citation: Neural Development 2014 9:16
  11. Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) regulate the survival of gustatory neurons, axon growth and branching, and innervation of taste buds during development. These actions are larg...

    Authors: Da Fei, Tao Huang and Robin F Krimm
    Citation: Neural Development 2014 9:15
  12. Xenopus laevis has regenerative and non-regenerative stages. As a tadpole, it is fully capable of functional recovery after a spinal cord injury, while its juvenile form (froglet) loses this capability during met...

    Authors: Dasfne Lee-Liu, Mauricio Moreno, Leonardo I Almonacid, Víctor S Tapia, Rosana Muñoz, Javier von Marées, Marcia Gaete, Francisco Melo and Juan Larraín
    Citation: Neural Development 2014 9:12

    The Related Article to this article has been published in Nature Protocols 2017 12:nprot.2016.177

  13. Proper binocular vision depends on the routing at the optic chiasm of the correct proportion of retinal ganglion cell (RGC) axons that project to the same (ipsilateral) and opposite (contralateral) side of the...

    Authors: Punita Bhansali, Ilana Rayport, Alexandra Rebsam and Carol Mason
    Citation: Neural Development 2014 9:11
  14. Morphogenesis of the zebrafish neural tube requires the coordinated movement of many cells in both time and space. A good example of this is the movement of the cells in the zebrafish neural plate as they conv...

    Authors: Claudio Araya, Marcel Tawk, Gemma C Girdler, Marta Costa, Carlos Carmona-Fontaine and Jonathan DW Clarke
    Citation: Neural Development 2014 9:9
  15. As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b. The shared presence of four specific amino acid motifs—M1 to M4—in the N-terminal region of mamm...

    Authors: Alejandro Pinzón-Olejua, Cornelia Welte, Houari Abdesselem, Edward Málaga-Trillo and Claudia AO Stuermer
    Citation: Neural Development 2014 9:8
  16. Latrophilins (LPHNs) are a small family of neuronal adhesion-GPCRs originally discovered as receptors for the black widow spider toxin α-latrotoxin. Mutations in LPHN3 have recently been identified as risk factor...

    Authors: Matthew L O’Sullivan, Francesca Martini, Sventja von Daake, Davide Comoletti and Anirvan Ghosh
    Citation: Neural Development 2014 9:7
  17. The genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poor...

    Authors: Matthew J Eckler, Kathryn A Larkin, William L McKenna, Sol Katzman, Chao Guo, Robin Roque, Axel Visel, John L L Rubenstein and Bin Chen
    Citation: Neural Development 2014 9:6
  18. Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is req...

    Authors: Biliana O Veleva-Rotse, James L Smart, Annette F Baas, Benjamin Edmonds, Zi-ming Zhao, Allyson Brown, Lillian R Klug, Kelly Hansen, Gabrielle Reilly, Alexandria P Gardner, Krishnaveni Subbiah, Eric A Gaucher, Hans Clevers and Anthony P Barnes
    Citation: Neural Development 2014 9:5
  19. Vertebrates and invertebrates obtain visual motion information by channeling moving visual cues perceived by the retina through specific motion sensitive synaptic relays in the brain. In Drosophila, the series of...

    Authors: Carlos Oliva, Ching-Man Choi, Laura J J Nicolai, Natalia Mora, Natalie De Geest and Bassem A Hassan
    Citation: Neural Development 2014 9:4
  20. There are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene. This functional specificity is derived from distinct RGC ...

    Authors: Jason W Triplett, Wei Wei, Cristina Gonzalez, Neal T Sweeney, Andrew D Huberman, Marla B Feller and David A Feldheim
    Citation: Neural Development 2014 9:2
  21. The functional integration of the cerebellum into a number of different neural systems is governed by the connection of its output axons. In amniotes, the majority of this output is mediated by an evolutionari...

    Authors: Mary J Green and Richard JT Wingate
    Citation: Neural Development 2014 9:1
  22. The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. It is well known ...

    Authors: Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé
    Citation: Neural Development 2013 8:25
  23. The dorsal lateral geniculate nucleus (dLGN) of the mouse thalamus has emerged as a powerful experimental system for understanding the refinement of developing sensory connections. Interestingly, many of the b...

    Authors: Tania A Seabrook, Thomas E Krahe, Gubbi Govindaiah and William Guido
    Citation: Neural Development 2013 8:24
  24. During the EMBO course ‘Imaging of Neural Development in Zebrafish’, held on September 9–15th 2013, researchers from different backgrounds shared their latest results, ideas and practical expertise on zebrafish a...

    Authors: Steffen Scholpp, Lucia Poggi and Mihaela Žigman
    Citation: Neural Development 2013 8:23
  25. Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution assays have established that the XMAP215/Dis1/TOG family of MT regulators function as MT ‘plus-e...

    Authors: Laura Anne Lowery, Alina Stout, Anna E Faris, Liya Ding, Michelle A Baird, Michael W Davidson, Gaudenz Danuser and David Van Vactor
    Citation: Neural Development 2013 8:22
  26. Hearing depends on correct functioning of the cochlear hair cells, and their innervation by spiral ganglion neurons. Most of the insight into the embryological and molecular development of this sensory system ...

    Authors: Heiko Locher, Johan HM Frijns, Liesbeth van Iperen, John CMJ de Groot, Margriet A Huisman and Susana M Chuva de Sousa Lopes
    Citation: Neural Development 2013 8:20
  27. The conserved habenular neural circuit relays cognitive information from the forebrain into the ventral mid- and hindbrain. In zebrafish, the bilaterally formed habenulae in the dorsal diencephalon are made up...

    Authors: Carlo A Beretta, Nicolas Dross, Peter Bankhead and Matthias Carl
    Citation: Neural Development 2013 8:19
  28. Circuit formation in the nervous system essentially relies on the proper development of neurons and their processes. In this context, the ubiquitin ligase Nedd4 is a crucial modulator of axonal and dendritic b...

    Authors: Michael J Schmeisser, Susanne J Kühl, Michael Schoen, Nathalie H Beth, Tobias M Weis, Andreas M Grabrucker, Michael Kühl and Tobias M Boeckers
    Citation: Neural Development 2013 8:18
  29. Neurons in sympathetic ganglia and neuroendocrine cells in the adrenal medulla share not only their embryonic origin from sympathoadrenal precursors in the neural crest but also a range of functional features....

    Authors: Jutta Stubbusch, Priyanka Narasimhan, Katrin Huber, Klaus Unsicker, Hermann Rohrer and Uwe Ernsberger
    Citation: Neural Development 2013 8:16
  30. Spinal commissural axons represent a model system for deciphering the molecular logic that regulates the guidance of midline-crossing axons in the developing central nervous system (CNS). Whether the same or s...

    Authors: Tracy S Tran, Edward Carlin, Ruihe Lin, Edward Martinez, Jane E Johnson and Zaven Kaprielian
    Citation: Neural Development 2013 8:15
  31. During cerebral cortex development, multipotent neural progenitor cells generate a variety of neuronal subtypes in a fixed temporal order. How a single neural progenitor cell generates the diversity of cortica...

    Authors: Nathalie Saurat, Therese Andersson, Navneet A Vasistha, Zoltan Molnar and Frederick J Livesey
    Citation: Neural Development 2013 8:14
  32. In order to fulfill their chemosensory function, olfactory neurons are in direct contact with the external environment and are therefore exposed to environmental aggressive factors. Olfaction is maintained thr...

    Authors: Marie Paschaki, Laura Cammas, Yuko Muta, Yoko Matsuoka, Siu-Shan Mak, Monika Rataj-Baniowska, Valurie Fraulob, Pascal Dolle and Raj K Ladher
    Citation: Neural Development 2013 8:13
  33. The neural crest (NC) is a transient embryonic structure unique to vertebrates, which generates peripheral sensory and autonomic neurons, glia, neuroendocrine chromaffin and thyroid C-cells, melanocytes, and m...

    Authors: Stella Shtukmaster, Marie Catherine Schier, Katrin Huber, Shlomo Krispin, Chaya Kalcheim and Klaus Unsicker
    Citation: Neural Development 2013 8:12
  34. The conserved Caenorhabditis elegans proteins NID-1/nidogen and PTP-3A/LAR-RPTP function to efficiently localize the presynaptic scaffold protein SYD-2/α-liprin at active zones. Loss of function in these molecule...

    Authors: Raymond C Caylor, Yishi Jin and Brian D Ackley
    Citation: Neural Development 2013 8:10
  35. Teleost fish display widespread post-embryonic neurogenesis originating from many different proliferative niches that are distributed along the brain axis. During the development of the central nervous system ...

    Authors: Jan Kaslin, Volker Kroehne, Francesca Benato, Francesco Argenton and Michael Brand
    Citation: Neural Development 2013 8:9
  36. During cerebral cortical development, neural precursor-precursor interactions in the ventricular zone neurogenic niche coordinate signaling pathways that regulate proliferation and differentiation. Previous st...

    Authors: Jianing Zhang, Julie R Shemezis, Erin R McQuinn, Jing Wang, Maria Sverdlov and Anjen Chenn
    Citation: Neural Development 2013 8:7
  37. The central complex is a multimodal information-processing center in the insect brain composed of thousands of neurons representing more than 50 neural types arranged in a stereotyped modular neuroarchitecture...

    Authors: Nadia Riebli, Gudrun Viktorin and Heinrich Reichert
    Citation: Neural Development 2013 8:6
  38. Morphogenesis requires developmental processes to occur both at the right time and in the right place. During neural tube formation in the zebrafish embryo, the generation of the apical specializations of the ...

    Authors: Gemma C Girdler, Claudio Araya, Xiaoyun Ren and Jonathan DW Clarke
    Citation: Neural Development 2013 8:5


Chris Doe
University of Oregon, USA

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