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Correction: Lrig1 expression identifies quiescent stem cells in the ventricular‑subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation

The Original Article was published on 11 January 2023

Correction: Neural Dev 18, 1 (2023)

https://doi.org/10.1186/s13064-022-00169-1

The authors would like to correct errors and update two figures in the original publication of the article [1].

1. Page 2, “All mouse lines were backcrossed for at least 6 generations” corrected to “All mouse lines were backcrossed for at least 4 generations”.

2. Page 4, “0.1 M boric acid pH 8” corrected to “0.1 M sodium borate pH 8”.

3. Page 4, after “RFP goat polyclonal Rockland Immunochemicals 200-101-379 1:500” and before “RFP rabbit polyclonal Rockland Immunochemicals 600-401-379 1:500”, addition of “RFP guinea pig polyclonal Frontier Institute MSFR105900 1:500”.

4. Page 4, “To our knowledge, this mouse line was not previously characterized.” corrected to “To our knowledge, this mouse line was not previously characterized in detail.”.

5. Page 6, “KI-67 + ASCL1 + EGFP + cells, 3373 ± 532 cells per mm2” corrected to “EGFP + KI-67 + ASCL1 + cells, 3373 ± 532 cells per mm2”.

6. Page 6, “Consistent with the notion that the EGFP + KI-67- ASCL1- cells are quiescent B1 type stem cells” corrected to “Consistent with the notion that at least some of the EGFP + KI-67- ASCL1- cells are quiescent B1 type stem cells”.

7. Page 12, “all of the RFP + postnatal radial glial cells had cell body under the ventricular wall and contacted the ventricle with an apical extension (Fig. 6C).” corrected to “almost all of the RFP + postnatal radial glial cells had cell body under the ventricular wall and contacted the ventricle with an apical extension (Fig. 6C).”

8. Figure 3 was updated.

Fig. 3
figure 1

The rare EdU label-retaining Lrig1-expressing cells. A-C The rare RFP+ EdU+ cells were identified from low magnification confocal scans then imaged again with a high magnification objective at the confocal. Scale bar, 10 μm

9. Figure 6 was updated.

Fig. 6
figure 2

The Lrig1-expressing cells in the postnatal brain lateral wall. A RFP+ postnatal radial glial cells from tamoxifen induction during postnatal development. Scale bar, 10 μm. B VCAM1 expression in an RFP+ cell. Scale bar, 10 μm. C An RFP+ KI-67- cell. Scale bar, 10 μm. D Two distinct morphotypes at juvenile age after postnatal tamoxifen induction. Scale bar, 10 μm. E Two distinct morphotypes at young adult age after postnatal tamoxifen induction. Scale bar, 10 μm. F Unbranched RFP+ postnatal radial glial cells. Scale bar, 10 μm. G Branched RFP+ postnatal radial glial cells. Scale bar, 10 μm

Reference

  1. Nam HS, Capecchi MR. Lrig1 expression identifies quiescent stem cells in the ventricular-subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation. Neural Dev. 2023;18(1):1.

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Correspondence to Hyung-song Nam.

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Nam, Hs., Capecchi, M.R. Correction: Lrig1 expression identifies quiescent stem cells in the ventricular‑subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation. Neural Dev 18, 4 (2023). https://doi.org/10.1186/s13064-023-00172-0

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  • DOI: https://doi.org/10.1186/s13064-023-00172-0