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Fig. 2 | Neural Development

Fig. 2

From: Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord

Fig. 2

Neuroprogenitor migration in Ntn1, Dcc, and Robo3 knockouts. a Cross sections of the spinal cord electroporated with Actb-gfp (βactin-gfp). The closeup images are of the boxed area. The embryos were cultured for 26 h. Some GFP+ neurons from the KOs are able to exit the VZ (PAX3/7+ area) after 26 h. b Quantification of the ratio between GFP+ neurons within the VZ and the total GFP+ neurons. A higher percentage of GFP+ neurons is seen within the VZ in the KOs than in controls. Data are represented as the mean ± SEM (Student’s t-test; **, p < 0.001; *, p < 0.05). Scale bars, 50 μm

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