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Table 3 Summary of cell cycle parameters

From: Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex

 

Rostral telencephalon

Caudal telencephalon

Difference

Cell cycle parameter

Wt (h)

+/E (h)

%Wt

Wt (h)

+/E (h)

%Wt

Wt versus +/E

Growth fraction

0.99

0.99

100

0.98

0.96

98

 

Time to reach max. LI

10.10

9.70

96

10.44

8.77

84

-1 hr 40 min

TC

13.32

13.31

100

13.35

11.74

88

-1 hr 37 min

TS

3.22

3.62

112

2.91

2.97

102

4 min

TG2+M

   

2.0

2.0

100

4 min

TM

   

0.80

0.87

109

4 min

TG2

   

1.2

1.13

94

 

TG1

   

8.44

6.77

80

-1 hr 40 min

  1. Cell cycle parameters were determined in the rostral and caudal regions of the EIIa-Cre;Fgfr3+/K644E(+/E) and wild type (Wt) littermate cortical primordium at E12.5. Four embryos per genotype and two counting boxes per sample were used at each time point. TG1, TG2, and TM were determined only in the caudal region where a difference in Tc was observed. Three embryos per genotype and one to two counting boxes per sample were used.
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Neural Development

ISSN: 1749-8104