Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex

Table 2 Summary of measurements of the PMBSF position in Foxg1-Cre;Fgfr3^+/K644M

Measurement	Cont ± SD	n	Fox+/M ± SD	n	%Cont	P-value
Rostrocaudal
Total length (T) (mm)	6.70 ± 0.51	7	7.42 ± 0.53	9	110.7	0.017
Frontal length (F) (mm)	3.75 ± 0.50	7	3.30 ± 0.44	9	88.0	NS
Occipital length (O) (mm)	2.84 ± 0.38	7	4.23 ± 0.24	9	148.9	1.0 × 10^-5
Ratio F/T	0.56 ± 0.055	7	0.44 ± 0.032	9	78.6	8.0 × 10^-4
Ratio O/T	0.42 ± 0.061	7	0.57 ± 0.023	9	132.6	4.6 × 10^-4
Lateromedial
Total width (W) (mm)	5.09 ± 0.70	7	4.86 ± 0.52	9	95.5	NS
Medial length (M) (mm)	2.37 ± 0.58	7	1.90 ± 0.26	9	80.2	NS
Lateral length (L) (mm)	2.73 ± 0.28	7	3.27 ± 0.61	9	119.8	0.038
Ratio M/W	0.46 ± 0.072	7	0.39 ± 0.074	9	84.8	NS
Ratio L/W	0.54 ± 0.073	7	0.67 ± 0.068	9	124.1	4.3 × 10^-3

Measurements were taken, as indicated in Figure 1c,i, to determine the rostrocaudal and lateromedial positions of the posteromedial barrel subfield (PMBSF) in Foxg1-Cre;Fgfr3^+/K644M(Fox+/M) and its littermate control (Cont) cortices at postnatal day 6.5. Results werare presented in the graph in Figure 2c-g (rostrocaudal) and 2h-l (lateromedial positions). SD, standard deviation.

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