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Figure 7 | Neural Development

Figure 7

From: Neural tube derived Wnt signals cooperate with FGF signaling in the formation and differentiation of the trigeminal placodes

Figure 7

Addition of fibroblast growth factor (FGF) or Wnt3A results in a similar expression of Islet1 in the ectoderm compared to the addition of Wnt3A and FGF8 together. In situ hybridization of Islet1 (blue) (A-F) of explants grown over night in culture. Explants in (A, C, E) were left untreated. Treated explants were grown in the presence of FGF8 (B), Wnt3A (D) and Wnt3A and FGF8 (F). FGF8 (B) or Wnt3A (D) addition resulted in a larger domain of Islet1 expression compared to controls (A, C). Addition of both Wnt3A and FGF8 (F) did not result in an increase in the domain of Islet1 expression compared to either ligand alone.

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Neural Development

ISSN: 1749-8104