Gene Symbol | Interneuron Marker | Interneuron Neurotransmitter Phenotype | Hurdle Model Statistical Data | ANOVA Statistical Data | ||||
---|---|---|---|---|---|---|---|---|
Least Squares Mean Reads | Fold-Change: Mutant 3 vs All Other Groups | Least Squares Mean Reads | Fold-Change: Mutant 3 vs All Other Groups | |||||
Mutant Group 3 | All Other Groups | Mutant Group 3 | All Other Groups | |||||
gata2a | KA’, KA”, and V2b | Inhibitory | 1.95 | 1.01 | ↑1.94*** | 70.63 | 1.40 | ↑50.50*** |
gata3 | KA’, KA”, and V2b | Inhibitory | 2.34 | 1.01 | ↑2.32*** | 154.55 | 1.80 | ↑85.98*** |
tal1 | KA’, KA”, and V2b | Inhibitory | 2.74 | 1.03 | ↑2.65*** | 138.08 | 2.68 | ↑51.44*** |
sst1.1 | KA” | Inhibitory | N.C. | N.C. | N.C. | 166.67 | 1.00 | ↑166.67*** |
en1b | V1 | Inhibitory | 8.36 | 1.01 | ↑8.26*** | 457.91 | 1.56 | ↑294.43*** |
dmrt3a | dI6 | Inhibitory | 2.77 | 1.02 | ↑2.71*** | 275.63 | 2.71 | ↑101.77*** |
lbx1a | dI4, dI5, and dI6 | Inhibitory (dI4, dI6) Excitatory (dI5) | 1.93 | 1.01 | ↑1.91*** | 59.87 | 1.72 | ↑34.78*** |
islet1a | Motoneurons | Acetylcholinergic | 1.29 | 1.01 | ↑1.28*** | 21.25 | 1.69 | ↑12.58*** |
islet2a | Motoneurons | Acetylcholinergic | 1.46 | 1.01 | ↑1.45*** | 54.58 | 1.56 | ↑35.06*** |
islet2b | Motoneurons | Acetylcholinergic | 1.21 | 1.00 | ↑1.21*** | 18.15 | 1.32 | ↑13.73*** |
mnx1 | Motoneurons | Acetylcholinergic | 1.42 | 1.00 | ↑1.42*** | 36.21 | 1.16 | ↑31.19*** |
mnx2a | Motoneurons | Acetylcholinergic | N.C. | N.C. | N.C. | 15.16 | 1.00 | ↑15.16*** |
mnx2b | Motoneurons | Acetylcholinergic | 1.41 | 1.03 | ↑1.37*** | 25.61 | 3.66 | ↑6.99*** |
sim1a | V3 | Excitatory | 1.00 | 1.00 | ↓1.00 | 1.00 | 1.30 | ↓1.30 |
vsx2 | V2a | Excitatory | 1.12 | 1.02 | ↑1.10 | 15.06 | 3.26 | ↑4.62 |
tlx3b | dI3 and dI5 | Excitatory | N.C | N.C | N.C | 2.11 | 1.00 | ↑2.11** |
foxp2 | dI2 | Excitatory | 1.19 | 1.16 | ↑1.03 | 19.54 | 10.47 | ↑1.87 |
barhl2 | dI1 | Excitatory | N.C. | N.C. | N.C. | 1.00 | 1.73 | ↓1.73 |