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Fig. 4 | Neural Development

Fig. 4

From: Dpr10 and Nocte are required for Drosophila motor axon pathfinding

Fig. 4

Loss of nocte causes stalling of ISNb before reaching terminal muscle targets. (A-C) Stage 16 embryo fillets stained for FasII (labels nerves, green) and phalloidin (labels muscles, magenta). Scale bar = 100 μm. (A′-C′) Insets from A-C (cyan rectangle), expanded to show ISNb terminal extension. (A′-C″) FasII stain of previous insets. Asterisk indicates terminal that reached and stalled at m13, arrowhead indicates terminal that traversed m13 and reached m12, and arrow indicates terminal that innervated m12. (D) Schematic of ISNb nerve terminals reaching or innervating m13 and m12. (E) Quantification of ISNb terminal position of genotypes in A-C. The bar graphs are represented as parts of a whole with the key given in D. Note that in noctep embryos the ISNb stalls at m13 with greater frequency than in either control or overexpression contexts (black bar)

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