Fig. 2
From: An inducible Cre mouse line to sparsely target nervous system cells, including Remak Schwann cells
ECSF mice sparsely label Remak Schwann cells. a ECSF; Ai14 mice were injected with tamoxifen or vehicle and the sciatic nerves immunostained for Remak Schwann cells (p75NTR, green) and nuclei (DAPI, blue). TdTomato is undetectable in vehicle-injected mice (top) and induced sparsely in Remak Schwann cells by tamoxifen (middle). Boxed area is enlarged to depict targeted (arrowheads) and untargeted (arrows) Remak Schwann cells (bottom). Note that the perineurium surrounding the nerve is also labeled. Scales bars = 50 μm. b Quantification of cells in (a) shows 15.96% of Remak Schwann cells are targeted in tamoxifen-injected mice. Three mice; 5 sections/mouse; error bar, standard error of mean