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Table 1 Description of the MoD in the three models with loss of proliferative capacity

From: Timing the spinal cord development with neural progenitor cells losing their proliferative capacity: a theoretical analysis

MoD

Type

Effect

Present in model

G→(G,G)

Symmetric proliferative

Proliferative

GGA, GAA, GAN

G→(G,A)

Asymmetric self-renewing

Proliferative

GGA

G→(A,A)

Symmetric consumptive

Proliferative

GAA

G→(A,N)

Asymmetric consumptive

Neurogenic

GAN

G→(N,N)

Symmetric consumptive

Neurogenic

PN

A→(A,N)

Asymmetric self-renewing

Neurogenic

GGA, GAA, GAN

A→(N,N)

Symmetric consumptive

Neurogenic

GGA, GAA, GAN

  1. In symmetric divisions, the two daughter cells display the same identity. In asymmetric divisions, the two daughter cells have different identities. In self-renewing divisions, one of the daughter cells has the same identity as the mother cell. In consumptive divisions, the two daughter cells differ in identity from the mother cell. In neurogenic divisions, at least one daughter cell is a neuron