Fig. 9
From: FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord
FGF8 promotes OPC specification following a Shh-dependent process. a-b Immunodetection of Olig2 (red in a and b, a', b') and Nkx2.2 (blue in a and b, a'', b'') on transverse sections of spinal cord explants cultivated for 2 days after electroporation of the control vector (green in a) or the FGF8 vector (green in b) at E4-E4.5. c-d Immunodetection of Olig2 (red in c and d, c', d') and Nkx2.2 (blue in c and d, c'', d'') on transverse sections of spinal cord explants electroporated with the control vector (green in c) or the FGF8 vector (green in d) and cultivated for 2 days in presence of cyclopamine. Scale bars = 50 μm