Fig. 4

Proximal axotomy in Class IV ddaC neurons induces regeneration of an axon from a dendrite. a An axon of a Class IV ddaC neuron was axotomized very close to the cell body (orange arrow) and imaged 2 h after injury. b The same neuron was imaged 96 h after injury to track regeneration. White arrows indicate a dendrite that has been converted to an axon. The identity of the new axon was confirmed by its plus-end-out microtubule polarity. c All 13 axotomized neurons converted a dendrite to an axon following proximal axotomy