Fig. 4

Conditional inactivation of Gsx2 in the septum by Olig2 ^Cre/+. (a, b) Gsx2 protein was lost in the septum and vLGE of the E15.5 Gsx2 cKO embryos, however its expression was relatively normal in the Gsx2 cKO dLGE. Insets in (a) and (b) represent low magnification DAPI stains (a’, b’). Dashed boxes in (a’) and (b’) represent the magnification in (a) and (b). (c, d) Accordingly, the Gsx2 family member, Gsx1 was found upregulated in the E15.5 Gsx2 cKO septum and vLGE