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Fig. 2 | Neural Development

Fig. 2

From: Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons

Fig. 2

L1 labelled forebrain axonal tracts are abnormal in Pax6 −/− embryos. Immunohistochemistry for axonal marker L1 labels axonal tracts at E14.5 (a, b), E16.5 (c, d) and E18.5 (e, f). In Pax6 +/+ embryos TCAs and corticofugal axons can be observed running between the thalamus and cortex (a, c, e). In Pax6 −/− embryos L1 labels an axon tract within the ventral telencephalon which increases in size between E14.5 and E18.5 (b, d, f). g, h Boxes mark the approximate areas shown in (a–f). Scale bar: 500 μm

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Neural Development

ISSN: 1749-8104