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Table 1 N-Cre: Mbd3 flox/flox peri-natal mortality

From: The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

 

Percentage (%)

d.p.c.

N-Cre: Mbd3 Flox/+

Mbd3 Flox/+

Mbd3 Flox/Flox

N-Cre: Mbd3 Flox/Flox

N

12.5

25

12.5

25

20.8

24

14.5

25.9

25.9

14.8

22.2

27

15.5

50

25

12.5

12.5

16

16.5

17.5

35

29.1

14.6

57

17.5

36.4

18.2

22.7

22.7

22

Postnatal

28.4

40.8

29.6

0.8a

250

  1. aAll N-Cre:Mbd3 Flox/Flox mice born live were found dead within 24 h after birth. Genotypes of pups and embryos produced from N-Cre(Flox/+) × (Flox/Flox) intercrosses recovered at indicated time points.
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Neural Development

ISSN: 1749-8104