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Figure 7 | Neural Development

Figure 7

From: Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex

Figure 7

Forced expression of Bacurd2:Rnd2 impairs radial migration in vivo . (A) Illustration of the protein resulting comprising the N-terminal region of Bacurd2(1-220) together with the C-terminal region of Rnd2 which mediates the migration of embryonic cortical neurons in vivo [7]. (B) Forced expression of Bacurd2:Rnd2 impairs cell migration within the embryonic E17.5 cortex, as do cells which overexpress either Bacurd2 or Rnd2 (N > 2,400 cells counted from three to four brains per condition; F 6,63 = 55.34; P < 0.0001; two-way ANOVA followed by Bonferroni’s post hoc test). Scale bar, 100 μm.

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Neural Development

ISSN: 1749-8104