Figure 7

Hybrid TrkB^−/−/ p75^−/−mice have many un-innervated taste buds at birth. Keratin 8-labeled (green) and P2X3-labeled (red) tongue sections from (A) a p75^−/−and (B) a TrkB^−/−/p75^−/−mouse. Whereas the p75^−/−mouse had both innervated (D) and un-innervated (C) taste buds, the TrkB^−/−/p75^−/−mouse had mostly un-innervated taste buds (E,F). Scale bar = 100 μm for A and B; scale bar = 10 μm for C-F.