Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling

Table 1 Summary of photoreceptor and cone cell quantifications from Pros and dPax2 genetic manipulations

Genotype	Mean number	n	Standard deviation	Significance
CC quantification
pros¹⁷/pros¹⁷	3.83	129	0.04	**
spa^pol/spa^pol	3.14	126	3.31	**
pros¹⁷ /+;spa^pol /spa^pol	2.10	109	0.01	**
sev>dPax2^RNAi + pros^RNAi	ND	-	-	-
sev>dPax2	4.15	129	0.05	*
sev>Pros	4.54	114	0.15	**
sev>Pros + dPax2	5.08	121	0.09	**
sev>Pros; spa^pol/spa^pol	0.00	143	0.00	-
sev>dPax2 + pros^RNAi	4.65	103	0.06	**
PR quantification
pros¹⁷/pros¹⁷	7.93	129	0.03	NS
spa^pol/spa^pol	7.95	126	0.00	NS
sev>dPax2	7.81	129	0.03	**
sev>Pros	8.15	114	0.06	**
sev-Ras^v12	8.65	202	0.07	**
sev>Pros + dPax2	8.02	121	0.01	NS
sev>Pros; spa^pol/spa^pol	11.00	143	0.03	**
sev>dPax2 + pros^RNAi	7.22	103	0.05	**

Statistical differences from wild-type numbers were analyzed by one-way ANOVA. *P < 0.05, **P < 0.001; NS, not significant; ND, not determined.

ISSN: 1749-8104