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Table 4 Heart rate changes after sequential administration of a muscarinic receptor and a beta-adrenergic receptor blocker

From: Nav2 is necessary for cranial nerve development and blood pressure regulation

 

Baseline

Glycopyrrolate

Δ

Propranolol

Δ

Wild type

489 ± 22

526 ± 15

37 ± 16

448 ± 10

78 ± 15

Homozygote

522 ± 17

563 ± 17

41 ± 13

453 ± 19

110 ± 7

  1. There is no significant difference between homozygous mutant and wild-type heart rate changes with either glycopyrrolate or propranolol. Values are mean ± standard error of the mean.