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Figure 10 | Neural Development

Figure 10

From: Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum

Figure 10

Spatiotemporal relationship between Purkinje plate formation and Reelin expression. (A-H) Comparison of the distribution of Corl2-expressing Purkinje cells (magenta) with that of Reelin (CR50; green) (A, E), ApoER2 mRNA (B, F), VLDLR mRNA (C, G), or mDab1 mRNA (D, H) in normal cerebella at E13.5 (A-D) and E14.5 (E-H). Purkinje cells just prior to initiating the formation of the PP, are clearly positive for VLDLR and mDab1 (and also for ApoER2 weakly) at E13.5, and the PP (arrow) emerges beneath the Reelin-rich zone (green), with intense signals for ApoER2, VLDLR, and mDab1 at E14.5.

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Neural Development

ISSN: 1749-8104