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  1. Research article

    Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick

    The cranial sensory ganglia represent populations of neurons with distinct functions, or sensory modalities. The production of individual ganglia from distinct neurogenic placodes with different developmental ...

    Cedric Patthey, Harry Clifford, Wilfried Haerty, Chris P. Ponting, Sebastian M. Shimeld and Jo Begbie

    Neural Development 2016 11:3

    Published on: 27 January 2016

  2. Research article

    Microtubule-associated protein 1b is required for shaping the neural tube

    Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the neural tissue, concomitantly with other morphogenetic changes that contribue to this process. In...

    Pradeepa Jayachandran, Valerie N. Olmo, Stephanie P. Sanchez, Rebecca J. McFarland, Eudorah Vital, Jonathan M. Werner, Elim Hong, Neus Sanchez-Alberola, Aleksey Molodstov and Rachel M. Brewster

    Neural Development 2016 11:1

    Published on: 18 January 2016

  3. Research article

    Deltex1 is inhibited by the Notch–Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation

    Notch signaling has been conserved throughout evolution and plays a fundamental role in various neural developmental processes and the pathogenesis of several human cancers and genetic disorders. However, how ...

    Yi-Chuan Cheng, Yin-Cheng Huang, Tu-Hsueh Yeh, Hung-Yu Shih, Ching-Yu Lin, Sheng-Jia Lin, Ching-Chi Chiu, Ching-Wen Huang and Yun-Jin Jiang

    Neural Development 2015 10:28

    Published on: 30 December 2015

  4. Research article

    Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons

    In the auditory brainstem, ventral cochlear nucleus (VCN) axons project to the contralateral, but not ipsilateral, medial nucleus of trapezoid body (MNTB), terminating in the calyx of Held. Dorsal VCN neurons,...

    Mariam L. Abdul-latif, Jesus A. Ayala Salazar, Sonya Marshak, Minhan L. Dinh and Karina S. Cramer

    Neural Development 2015 10:27

    Published on: 15 December 2015

  5. Research Article

    Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons

    In mouse embryos, the Pax6 transcription factor is expressed in the progenitors of thalamic neurons but not in thalamic neurons themselves. Its null-mutation causes early mis-patterning of thalamic progenitors...

    James M. Clegg, Ziwen Li, Michael Molinek, Isabel Martín Caballero, Martine N. Manuel and David J. Price

    Neural Development 2015 10:26

    Published on: 31 October 2015

  6. Research article

    The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm

    In the visual system of most binocular vertebrates, the axons of retinal ganglion cells (RGCs) diverge at the diencephalic midline and extend to targets on both ipsi- and contralateral sides of the brain. Whil...

    Paolo Panza, Austen A. Sitko, Hans-Martin Maischein, Iris Koch, Matthias Flötenmeyer, Gavin J. Wright, Kenji Mandai, Carol A. Mason and Christian Söllner

    Neural Development 2015 10:23

    Published on: 22 October 2015

  7. Research article

    Developmental remodeling of relay cells in the dorsal lateral geniculate nucleus in the absence of retinal input

    The dorsal lateral geniculate nucleus (dLGN) of the mouse has been an important experimental model for understanding thalamic circuit development. The developmental remodeling of retinal projections has been t...

    Rana N. El-Danaf, Thomas E. Krahe, Emily K. Dilger, Martha E. Bickford, Michael A. Fox and William Guido

    Neural Development 2015 10:19

    Published on: 15 July 2015

  8. Research article

    A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors

    Nonsense mediated mRNA decay (NMD) is an RNA surveillance mechanism that controls RNA stability and ensures the speedy degradation of erroneous and unnecessary transcripts. This mechanism depends on several co...

    Donghua Zou, Colleen McSweeney, Aswathy Sebastian, Derrick James Reynolds, Fengping Dong, Yijing Zhou, Dazhi Deng, Yonggang Wang, Long Liu, Jun Zhu, Jizhong Zou, Yongsheng Shi, Istvan Albert and Yingwei Mao

    Neural Development 2015 10:18

    Published on: 21 June 2015

  9. Research article

    Netrin-1 directs dendritic growth and connectivity of vertebrate central neurons in vivo

    Netrins are a family of extracellular proteins that function as chemotropic guidance cues for migrating cells and axons during neural development. In the visual system, netrin-1 has been shown to play a key ro...

    Anastasia N. Nagel, Sonya Marshak, Colleen Manitt, Rommel A. Santos, Marc A. Piercy, Sarah D. Mortero, Nicole J. Shirkey-Son and Susana Cohen-Cory

    Neural Development 2015 10:14

    Published on: 10 June 2015

  10. Research article

    The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

    Chromatin-modifying complexes have key roles in regulating various aspects of neural stem cell biology, including self-renewal and neurogenesis. The methyl binding domain 3/nucleosome remodelling and deacetyla...

    Erin Knock, João Pereira, Patrick D Lombard, Andrew Dimond, Donna Leaford, Frederick J Livesey and Brian Hendrich

    Neural Development 2015 10:13

    Published on: 2 May 2015

  11. Research article

    Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells

    Vertebrate retinal development is a complex process, requiring the specification and maintenance of retinal identity, proliferative expansion of retinal progenitor cells (RPCs), and their differentiation into ...

    Crystal L Sigulinsky, Massiell L German, Amanda M Leung, Anna M Clark, Sanghee Yun and Edward M Levine

    Neural Development 2015 10:12

    Published on: 27 April 2015

  12. Research article

    Dynamic regulation of mRNA decay during neural development

    Gene expression patterns are determined by rates of mRNA transcription and decay. While transcription is known to regulate many developmental processes, the role of mRNA decay is less extensively defined. A cr...

    Dana A Burow, Maxine C Umeh-Garcia, Marie B True, Crystal D Bakhaj, David H Ardell and Michael D Cleary

    Neural Development 2015 10:11

    Published on: 21 April 2015

  13. Research article

    Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder

    Autism spectrum disorders (ASD) are a group of poorly understood behavioural disorders, which have increased in prevalence in the past two decades. Animal models offer the opportunity to understand the biologi...

    Laura R Fenlon, Sha Liu, Ilan Gobius, Nyoman D Kurniawan, Skyle Murphy, Randal X Moldrich and Linda J Richards

    Neural Development 2015 10:10

    Published on: 3 April 2015

  14. Research article

    Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex

    During fetal brain development in mammals, newborn neurons undergo cell migration to reach their appropriate positions and form functional circuits. We previously reported that the atypical RhoA GTPase Rnd2 pr...

    Ivan Enghian Gladwyn-Ng, Shan Shan Li, Zhengdong Qu, John Michael Davis, Linh Ngo, Matilda Haas, Jeffrey Singer and Julian Ik-Tsen Heng

    Neural Development 2015 10:9

    Published on: 31 March 2015

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