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  1. The secreted ligand Reelin is believed to regulate the translocation of prospective layer 6 (L6) neocortical neurons into the preplate, a loose layer of pioneer neurons that overlies the ventricular zone. Rece...

    Authors: Ryan S O’Dell, Candida J M Ustine, David A Cameron, Sean M Lawless, Rebecca M Williams, Warren R Zipfel and Eric C Olson
    Citation: Neural Development 2012 7:25
    Content type: Research article Published on:

  2. Pannexin 1 forms ion and metabolite permeable hexameric channels and is abundantly expressed in the brain. After discovering pannexin 1 expression in postnatal neural stem and progenitor cells we sought to elu...

    Authors: Leigh E Wicki-Stordeur, Adrian D Dzugalo, Rose M Swansburg, Jocelyne M Suits and Leigh Anne Swayne
    Citation: Neural Development 2012 7:11
    Content type: Research article Published on:

  3. The pre B-cell leukemia transcription factor 1 (Pbx1) genes belong to the three amino acid loop extension family of homeodomain proteins that form hetero-oligomeric complexes with other homeodomain transcription ...

    Authors: Paola Sgadò, Elisabetta Ferretti, Daniel Grbec, Yuri Bozzi and Horst H Simon
    Citation: Neural Development 2012 7:24
    Content type: Research article Published on:

  4. The sensory neurons and glia of the dorsal root ganglia (DRG) arise from neural crest cells in the developing vertebrate embryo. In mouse and chick, DRG formation is completed during embryogenesis. In contrast...

    Authors: Hillary Faye McGraw, Corey D Snelson, Andrew Prendergast, Arminda Suli and David W Raible
    Citation: Neural Development 2012 7:23
    Content type: Research article Published on:

  6. During neocortical development, multiple voltage- and ligand-gated ion channels are differentially expressed in neurons thereby shaping their intrinsic electrical properties. One of these voltage-gated ion cha...

    Authors: Arne Battefeld, Nino Rocha, Konstantin Stadler, Anja U Bräuer and Ulf Strauss
    Citation: Neural Development 2012 7:21
    Content type: Research article Published on:

  7. Sulfated glycosaminoglycan chains are known for their regulatory functions during neural development and regeneration. However, it is still unknown whether the sulfate residues alone influence, for example, ne...

    Authors: Michael Karus, Samira Samtleben, Claudia Busse, Teresa Tsai, Irmgard D Dietzel, Andreas Faissner and Stefan Wiese
    Citation: Neural Development 2012 7:20
    Content type: Research Article Published on:

  8. Understanding the cellular mechanisms regulating axon degeneration and regeneration is crucial for developing treatments for nerve injury and neurodegenerative disease. In neurons, axon degeneration is distinc...

    Authors: Rosario Villegas, Seanna M Martin, Kelley C O’Donnell, Simon A Carrillo, Alvaro Sagasti and Miguel L Allende
    Citation: Neural Development 2012 7:19
    Content type: Research article Published on:

  9. Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While midline crossing is achieved through coordinated signaling of attractive and repulsiv...

    Authors: Jennifer Bonner, Michael Letko, Oliver Brant Nikolaus, Lisa Krug, Alexandria Cooper, Benjamin Chadwick, Phoebe Conklin, Amy Lim, Chi-Bin Chien and Richard I Dorsky
    Citation: Neural Development 2012 7:18
    Content type: Research Article Published on:

  10. The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant re...

    Authors: Thomas K Knott, Pasil A Madany, Ashley A Faden, Mei Xu, Jörg Strotmann, Timothy R Henion and Gerald A Schwarting
    Citation: Neural Development 2012 7:17
    Content type: Research Article Published on:

  13. In Drosophila, most neurogenetic research is carried out in vivo. Mammalian research demonstrates that primary cell culture techniques provide a powerful model to address cell autonomous and non-autonomous proces...

    Authors: Manuela M Moraru, Boris Egger, Diarra B Bao and Simon G Sprecher
    Citation: Neural Development 2012 7:14
    Content type: Methodology Published on:

  14. In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus) can regenerate their spinal cord after injury. However, the cellular and molecular mechanis...

    Authors: Marcia Gaete, Rosana Muñoz, Natalia Sánchez, Ricardo Tampe, Mauricio Moreno, Esteban G Contreras, Dasfne Lee-Liu and Juan Larraín
    Citation: Neural Development 2012 7:13
    Content type: Research article Published on:

    The Related Article to this article has been published in Nature Protocols 2017 12:nprot.2016.177

  15. A fundamental requirement for development of diverse brain regions is the function of local organizers at morphological boundaries. These organizers are restricted groups of cells that secrete signaling molecu...

    Authors: Benjamin Mattes, Sabrina Weber, João Peres, Qing Chen, Gary Davidson, Corinne Houart and Steffen Scholpp
    Citation: Neural Development 2012 7:12
    Content type: Research article Published on:

  16. Cortical GABAergic interneurons (INs) are generated in the medial ganglionic eminence (MGE) and migrate tangentially into cortex. Because most, if not all, migrating MGE-derived INs express the neuregulin (NRG...

    Authors: Hao Li, Shen-Ju Chou, Tadashi Hamasaki, Carlos G Perez-Garcia and Dennis DM O'Leary
    Citation: Neural Development 2012 7:10
    Content type: Research article Published on:

  17. The assembly of neural circuits requires the concerted action of both genetically determined and activity-dependent mechanisms. Calcium-regulated transcription may link these processes, but the influence of sp...

    Authors: Scott A Wilke, Benjamin J Hall, Joseph K Antonios, Laura A DeNardo, Stefanie Otto, Bo Yuan, Fading Chen, Elissa M Robbins, Katie Tiglio, Megan E Williams, Zilong Qiu, Thomas Biederer and Anirvan Ghosh
    Citation: Neural Development 2012 7:9
    Content type: Research article Published on:

  19. The sequestration of Muscleblind splicing regulators results in myotonic dystrophy. Previous work on Muscleblind has largely focused on its roles in muscle development and maintenance due to the skeletal and c...

    Authors: Kerri A Spilker, George J Wang, Madina S Tugizova and Kang Shen
    Citation: Neural Development 2012 7:7
    Content type: Research article Published on:

  20. Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans in embryonic neural environments suggests that ma...

    Authors: Jessica CF Kwok, Ying-Lai Yuen, Wai-Kit Lau, Fu-Xing Zhang, James W Fawcett, Ying-Shing Chan and Daisy KY Shum
    Citation: Neural Development 2012 7:6
    Content type: Research article Published on:

  23. The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death. Recently, novel neural stem cells that amplify neural proliferation thr...

    Authors: Yanrui Jiang and Heinrich Reichert
    Citation: Neural Development 2012 7:3
    Content type: Research article Published on:

  24. Tangential migration presents the primary mode of migration of cortical interneurons translocating into the cerebral cortex from subpallial domains. This migration takes place in multiple streams with the most...

    Authors: Konstantinos Zarbalis, Youngshik Choe, Julie A Siegenthaler, Lori A Orosco and Samuel J Pleasure
    Citation: Neural Development 2012 7:2
    Content type: Research article Published on:

  25. In the decapod crustacean brain, neurogenesis persists throughout the animal's life. After embryogenesis, the central olfactory pathway integrates newborn olfactory local and projection interneurons that repla...

    Authors: Silvia Sintoni, Jeanne L Benton, Barbara S Beltz, Bill S Hansson and Steffen Harzsch
    Citation: Neural Development 2012 7:1
    Content type: Research article Published on:

  26. Various members of the family of BTB/POZ zinc-finger transcription factors influence patterns of dendritic branching. One such member, Broad, is notable because its BrZ3 isoform is widely expressed in Drosophila ...

    Authors: Janet A Scott, Darren W Williams and James W Truman
    Citation: Neural Development 2011 6:39
    Content type: Research article Published on:

  28. The phylogenetically conserved transcription factor Lola is essential for many aspects of axon growth and guidance, synapse formation and neural circuit development in Drosophila. To date it has been difficult, h...

    Authors: Michael A Gates, Ramakrishnan Kannan and Edward Giniger
    Citation: Neural Development 2011 6:37
    Content type: Research article Published on:

  29. Bone morphogenetic protein (BMP)7 evokes both inductive and axon orienting responses in dorsal interneurons (dI neurons) in the developing spinal cord. These events occur sequentially during the development of...

    Authors: Jeanette C Perron and Jane Dodd
    Citation: Neural Development 2011 6:36
    Content type: Research article Published on:

  30. The size and cell number of each brain region are influenced by the organization and behavior of neural progenitor cells during embryonic development. Recent studies on developing neocortex have revealed the p...

    Authors: Lynn Wang, Krista K Bluske, Lauren K Dickel and Yasushi Nakagawa
    Citation: Neural Development 2011 6:35
    Content type: Research article Published on:

  31. The dopaminergic (DA) neurons present in the central brain of the Drosophila larva are spatially arranged in stereotyped groups that define clusters of bilaterally symmetrical neurons. These clusters have been cl...

    Authors: Jorge Blanco, Rahul Pandey, Martin Wasser and Gerald Udolph
    Citation: Neural Development 2011 6:34
    Content type: Research article Published on:

  32. The mechanisms that consolidate neural circuitry are a major focus of neuroscience. In the mammalian cochlea, the refinement of spiral ganglion neuron (SGN) innervation to the inner hair cells (by type I SGNs)...

    Authors: Meagan Barclay, Allen F Ryan and Gary D Housley
    Citation: Neural Development 2011 6:33
    Content type: Research article Published on:

  34. Neuronal output is shaped by a balance of excitation and inhibition. How this balance is attained in the central nervous system during development is not well understood, and is complicated by the fact that, in v...

    Authors: Florentina Soto, Adam Bleckert, Renate Lewis, Yunhee Kang, Daniel Kerschensteiner, Ann Marie Craig and Rachel OL Wong
    Citation: Neural Development 2011 6:31
    Content type: Research article Published on:

  36. The ventral midbrain contains a diverse array of neurons, including dopaminergic neurons of the ventral tegmental area (VTA) and substantia nigra (SN) and neurons of the red nucleus (RN). Dopaminergic and RN n...

    Authors: Sandra Blaess, Gabriela O Bodea, Anna Kabanova, Soline Chanet, Emilie Mugniery, Amin Derouiche, Daniel Stephen and Alexandra L Joyner
    Citation: Neural Development 2011 6:29
    Content type: Research article Published on:

  37. An essential stage of neural development involves the assembly of neural circuits via formation of inter-neuronal connections. Early steps in neural circuit formation, including cell migration, axon guidance, ...

    Authors: Joori Park, Philip Louis Knezevich, William Wung, Shanté Nicole O'Hanlon, Akshi Goyal, Kelli Leilani Benedetti, Benjamin James Barsi-Rhyne, Mekala Raman, Natalyn Mock, Martina Bremer and Miri Kerensa VanHoven
    Citation: Neural Development 2011 6:28
    Content type: Research article Published on:

  38. Development of specific neuronal morphology requires precise control over cell motility processes, including axon formation, outgrowth and branching. Dynamic remodeling of the filamentous actin (F-actin) cytos...

    Authors: Erica F Andersen, Namrata S Asuri and Mary C Halloran
    Citation: Neural Development 2011 6:27
    Content type: Research article Published on:

  39. Cytoplasmic dynein and its regulatory proteins have been implicated in neuronal and non-neuronal cell migration. A genetic model for analyzing the role of cytoplasmic dynein specifically in these processes has...

    Authors: Kassandra M Ori-McKenney and Richard B Vallee
    Citation: Neural Development 2011 6:26
    Content type: Research article Published on:

  40. The cerebellum is composed of a diverse array of neuronal subtypes. Here we have used a candidate approach to identify Zac1, a tumor suppressor gene encoding a zinc finger transcription factor, as a new player in...

    Authors: Seung-Hyuk Chung, Hassan Marzban, Kimberly Aldinger, Rajiv Dixit, Kathleen Millen, Carol Schuurmans and Richard Hawkes
    Citation: Neural Development 2011 6:25
    Content type: Research article Published on:

  43. Long-distance axonal growth relies on the precise interplay of guidance cues and cell adhesion molecules. While guidance cues provide positional and directional information for the advancing growth cone, cell ...

    Authors: Pascal Joset, Andrin Wacker, Régis Babey, Esther A Ingold, Irwin Andermatt, Esther T Stoeckli and Matthias Gesemann
    Citation: Neural Development 2011 6:22
    Content type: Research article Published on:

  44. Neurons form specific connections with targets via synapses and patterns of synaptic connectivity dictate neural function. During development, intrinsic neuronal specification and environmental factors guide b...

    Authors: Meredith A Clifford, Jessleen K Kanwal, Rhonda Dzakpasu and Maria J Donoghue
    Citation: Neural Development 2011 6:21
    Content type: Research article Published on:

  45. The concept of an equivalence group, a cluster of cells with equal potential to adopt the same specific fate, has served as a useful paradigm to understand neural cell type specification. In the Drosophila eye, a...

    Authors: Mark Charlton-Perkins, S Leigh Whitaker, Yueyang Fei, Baotong Xie, David Li-Kroeger, Brian Gebelein and Tiffany Cook
    Citation: Neural Development 2011 6:20
    Content type: Research article Published on:

  47. In the developing vertebrate peripheral nervous system, the survival of sympathetic neurons and the majority of sensory neurons depends on a supply of nerve growth factor (NGF) from tissues they innervate. Alt...

    Authors: Sean L Wyatt, Bodo Spori, Tom N Vizard and Alun M Davies
    Citation: Neural Development 2011 6:18
    Content type: Research article Published on:

Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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Neural Development

ISSN: 1749-8104