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  1. Otx genes, orthologues of the Drosophila orthodenticle gene (otd), play crucial roles in vertebrate brain development. In the Xenopus eye, Xotx2 and Xotx5b promote bipolar and photoreceptor cell fates, respective...

    Authors: Marco Onorati, Federico Cremisi, Yang Liu, Rong-Qiao He, Giuseppina Barsacchi and Robert Vignali
    Citation: Neural Development 2007 2:12
    Content type: Research article Published on:

  2. Organs are programmed to acquire a particular size during development, but the regulatory mechanisms that dictate when dividing progenitor cells should permanently exit the cell cycle and stop producing additi...

    Authors: Lin Ma, Robert Cantrup, Annie Varrault, Dilek Colak, Natalia Klenin, Magdalena Götz, Sarah McFarlane, Laurent Journot and Carol Schuurmans
    Citation: Neural Development 2007 2:11
    Content type: Research article Published on:

  3. Telencephalic patterning centers, defined by the discrete expression domains of distinct morphogens, Fgf s in the commissural plate (CoP), Wnt s and Bmp s in the cortical hem, and a ventral domain of Sonic hedgeh...

    Authors: Setsuko Sahara, Yasuhiko Kawakami, Juan Carlos Izpisua Belmonte and Dennis DM O'Leary
    Citation: Neural Development 2007 2:10
    Content type: Research article Published on:

  5. The forebrain consists of multiple structures necessary to achieve elaborate functions. Proper patterning is, therefore, a prerequisite for the generation of optimal functional areas. Only a few factors have b...

    Authors: Andreas Zembrzycki, Gundula Griesel, Anastasia Stoykova and Ahmed Mansouri
    Citation: Neural Development 2007 2:8
    Content type: Research article Published on:

  6. Proper neuronal function depends on forming three primary subcellular compartments: axons, dendrites, and soma. Each compartment has a specialized function (the axon to send information, dendrites to receive i...

    Authors: Melissa M Rolls, Daisuke Satoh, Peter J Clyne, Astra L Henner, Tadashi Uemura and Chris Q Doe
    Citation: Neural Development 2007 2:7
    Content type: Research article Published on:

  8. During the embryonic development of the cerebellum, neurons are produced from progenitor cells located along a ventricular zone within dorsal rhombomere 1 that extends caudally to the roof plate of the fourth ...

    Authors: Robert P Machold, Deborah Jones Kittell and Gordon J Fishell
    Citation: Neural Development 2007 2:5
    Content type: Research article Published on:

  9. Extracellular signaling through receptors for neurotrophins mediates diverse neuronal functions, including survival, migration and differentiation in the central nervous system, but the transcriptional targets...

    Authors: Anna Maria Calella, Claus Nerlov, Rodolphe G Lopez, Carla Sciarretta, Oliver von Bohlen und Halbach, Oksana Bereshchenko and Liliana Minichiello
    Citation: Neural Development 2007 2:4
    Content type: Research article Published on:

  10. General somatic sensation is conveyed to the central nervous system at cranial levels by the trigeminal ganglion (TG), and at spinal levels by the dorsal root ganglia (DRG). Although these ganglia have similar...

    Authors: S Raisa Eng, Iain M Dykes, Jason Lanier, Natalia Fedtsova and Eric E Turner
    Citation: Neural Development 2007 2:3
    Content type: Research article Published on:

  11. Modifications in Pax6 homeogene expression produce strong eye phenotypes. This suggested to us that eye development might be an appropriate model to verify if homeoprotein intercellular passage has important func...

    Authors: Brigitte Lesaffre, Alain Joliot, Alain Prochiantz and Michel Volovitch
    Citation: Neural Development 2007 2:2
    Content type: Research article Published on:

  12. The choice of a stem cell to divide symmetrically or asymmetrically has profound consequences for development and disease. Unregulated symmetric division promotes tumor formation, whereas inappropriate asymmet...

    Authors: Boris Egger, Jason Q Boone, Naomi R Stevens, Andrea H Brand and Chris Q Doe
    Citation: Neural Development 2007 2:1
    Content type: Research article Published on:

  14. While developmental processes such as axon pathfinding and synapse formation have been characterized in detail, comparatively less is known of the intrinsic developmental mechanisms that regulate transcription...

    Authors: Edward CG Pym, Tony D Southall, Christopher J Mee, Andrea H Brand and Richard A Baines
    Citation: Neural Development 2006 1:3
    Content type: Research article Published on:

  15. In the absence of external cues, neurons in vitro polarize by using intrinsic mechanisms. For example, cultured hippocampal neurons extend arbitrarily oriented neurites and then one of these, usually the one near...

    Authors: Flavio R Zolessi, Lucia Poggi, Christopher J Wilkinson, Chi-Bin Chien and William A Harris
    Citation: Neural Development 2006 1:2
    Content type: Research article Published on:

Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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Neural Development

ISSN: 1749-8104