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  1. Insm1 is a zinc-finger transcription factor transiently expressed throughout the developing nervous system in late progenitors and nascent neurons. Insm1 is also highly expressed in medulloblastomas and other ...

    Authors: Jason N Rosenbaum, Anne Duggan and Jaime García-Añoveros

    Citation: Neural Development 2011 6:6

    Content type: Research article

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  2. The dorsal thalamus acts as a gateway and modulator for information going to and from the cerebral cortex. This activity requires the formation of reciprocal topographic axon connections between thalamus and c...

    Authors: Noelle D Dwyer, Danielle K Manning, Jennifer L Moran, Raksha Mudbhary, Michael S Fleming, Carlita B Favero, Vita M Vock, Dennis DM O'Leary, Christopher A Walsh and David R Beier

    Citation: Neural Development 2011 6:3

    Content type: Research article

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  3. Newts have the remarkable ability to regenerate their spinal cords as adults. Their spinal cords regenerate with the regenerating tail after tail amputation, as well as after a gap-inducing spinal cord injury ...

    Authors: Katherine A Zukor, David T Kent and Shannon J Odelberg

    Citation: Neural Development 2011 6:1

    Content type: Research article

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  4. Nervous systems are generally bilaterally symmetric on a gross structural and organizational level but are strongly lateralized (left/right asymmetric) on a functional level. It has been previously noted that ...

    Authors: Andrew D Goldsmith, Sumeet Sarin, Shawn Lockery and Oliver Hobert

    Citation: Neural Development 2010 5:33

    Content type: Research article

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  5. In an effort to identify genes that specify the mammalian forebrain, we used a comparative approach to identify mouse homologs of transcription factors expressed in developing Caenorhabditis elegans GABAergic neu...

    Authors: Elizabeth AD Hammock, Kathie L Eagleson, Susan Barlow, Laurie R Earls, David M Miller III and Pat Levitt

    Citation: Neural Development 2010 5:32

    Content type: Research article

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  6. We previously identified four functionally distinct human NUMB isoforms. Here, we report the identification of two additional isoforms and propose a link between the expression of these isoforms and cancer. Th...

    Authors: Aldona Karaczyn, Mahmud Bani-Yaghoub, Roger Tremblay, Chris Kubu, Rebecca Cowling, Tamara L Adams, Igor Prudovsky, Douglas Spicer, Robert Friesel, Calvin Vary and Joseph M Verdi

    Citation: Neural Development 2010 5:31

    Content type: Research article

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  7. Retinotectal map formation develops via topographically specific guidance and branching of retinal axons in their target area. This process is controlled, in part, by reverse signalling of ephrinAs expressed o...

    Authors: Katharine JM Marler, Subathra Poopalasundaram, Emma R Broom, Corinna Wentzel and Uwe Drescher

    Citation: Neural Development 2010 5:30

    Content type: Research article

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  8. Many neurons in the central nervous system, including retinal ganglion cells (RGCs), possess asymmetric dendritic arbors oriented toward their presynaptic partners. How such dendritic arbors become biased duri...

    Authors: Jung-Hwan Choi, Mei-Yee Law, Chi-Bin Chien, Brian A Link and Rachel OL Wong

    Citation: Neural Development 2010 5:29

    Content type: Research article

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  9. The Hedgehog (Hh) signaling pathway is important for the development of a variety of tissues in both vertebrates and invertebrates. For example, in developing nervous systems Hh signaling is required for the n...

    Authors: Darius Camp, Ko Currie, Alain Labbé, Donald J van Meyel and Frédéric Charron

    Citation: Neural Development 2010 5:28

    Content type: Research article

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  10. The Notch signalling pathway plays crucial roles in neural development, functioning by preventing premature differentiation and promotion of glial cell fates. In the developing cerebellum Notch pathway compone...

    Authors: Elaine Julian, Andrew R Hallahan and Brandon J Wainwright

    Citation: Neural Development 2010 5:27

    Content type: Research article

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  11. Tissue homeostasis depends on the ability of stem cells to properly regulate self-renewal versus differentiation. Drosophila neural stem cells (neuroblasts) are a model system to study self-renewal and differenti...

    Authors: Omer Ali Bayraktar, Jason Q Boone, Michael L Drummond and Chris Q Doe

    Citation: Neural Development 2010 5:26

    Content type: Research article

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  12. In sensory systems with broad bandwidths, polarized receptor cells utilize highly specialized organelles in their apical and basolateral compartments to transduce and ultimately transmit signals to the rest of...

    Authors: George Zanazzi and Gary Matthews

    Citation: Neural Development 2010 5:24

    Content type: Research article

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  13. Cerebellar corticogenesis begins with the assembly of Purkinje cells into the Purkinje plate (PP) by embryonic day 14.5 (E14.5) in mice. Although the dependence of PP formation on the secreted protein Reelin i...

    Authors: Takaki Miyata, Yuichi Ono, Mayumi Okamoto, Makoto Masaoka, Akira Sakakibara, Ayano Kawaguchi, Mitsuhiro Hashimoto and Masaharu Ogawa

    Citation: Neural Development 2010 5:23

    Content type: Research article

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  14. During visual system development, multiple signalling pathways cooperate to specify axial polarity within the retina and optic tectum. This information is required for the topographic mapping of retinal gangli...

    Authors: Timothy Erickson, Curtis R French and Andrew J Waskiewicz

    Citation: Neural Development 2010 5:22

    Content type: Research article

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  15. Nolz1 is a zinc finger transcription factor whose expression is enriched in the lateral ganglionic eminence (LGE), although its function is still unknown.

    Authors: Noelia Urbán, Raquel Martín-Ibáñez, Cristina Herranz, Miriam Esgleas, Empar Crespo, Monica Pardo, Ivan Crespo-Enríquez, Héctor R Méndez-Gómez, Ronald Waclaw, Christina Chatzi, Susana Álvarez, Rosana Álvarez, Gregg Duester, Kenneth Campbell, Angel R de Lera, Carlos Vicario-Abejón…

    Citation: Neural Development 2010 5:21

    Content type: Research article

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  16. Olfactory sensory neuron (OSN) axons exit the olfactory epithelium (OE) and extend toward the olfactory bulb (OB) where they coalesce into glomeruli. Each OSN expresses only 1 of approximately 1,200 odor recep...

    Authors: Alexandra M Miller, Lydia R Maurer, Dong-Jing Zou, Stuart Firestein and Charles A Greer

    Citation: Neural Development 2010 5:20

    Content type: Research article

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  17. The active form (T3) of thyroid hormone (TH) controls critical aspects of cerebellar development, such as migration of postmitotic neurons and terminal dendritic differentiation of Purkinje cells. The effects of ...

    Authors: Fatiha Boukhtouche, Bernard Brugg, Rosine Wehrlé, Brigitte Bois-Joyeux, Jean-Louis Danan, Isabelle Dusart and Jean Mariani

    Citation: Neural Development 2010 5:18

    Content type: Research article

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  18. The ependyma, the lining providing a protective barrier and filtration system separating brain parenchyma from cerebrospinal fluid, is still inadequately understood in humans. In this study we aimed to define,...

    Authors: Anna M Lavezzi, Melissa F Corna and Luigi Matturri

    Citation: Neural Development 2010 5:17

    Content type: Research article

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  19. In the developing hindbrain, cranial motor axon guidance depends on diffusible repellent factors produced by the floor plate. Our previous studies have suggested that candidate molecules for mediating this eff...

    Authors: Ailish Murray, Arifa Naeem, Sarah H Barnes, Uwe Drescher and Sarah Guthrie

    Citation: Neural Development 2010 5:16

    Content type: Research article

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  20. The inhibitory neurotransmitter gamma-amino-butyric acid (GABA) not only modulates excitability in the mature nervous system but also regulates neuronal differentiation and circuit development. Horizontal cell...

    Authors: Timm Schubert, Rachel M Huckfeldt, Edward Parker, John E Campbell and Rachel OL Wong

    Citation: Neural Development 2010 5:15

    Content type: Research article

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  21. The mammalian amygdala is composed of two primary functional subdivisions, classified according to whether the major output projection of each nucleus is excitatory or inhibitory. The posterior dorsal and vent...

    Authors: Rosalind SE Carney, Jean-Marie Mangin, Lindsay Hayes, Kevin Mansfield, Vitor H Sousa, Gord Fishell, Robert P Machold, Sohyun Ahn, Vittorio Gallo and Joshua G Corbin

    Citation: Neural Development 2010 5:14

    Content type: Research article

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  22. Mouse definitive neural stem cells (NSCs) are derived from a population of LIF-responsive primitive neural stem cells (pNSCs) within the neurectoderm, yet details on the early signaling and transcriptional mec...

    Authors: Lan TH Dang and Vincent Tropepe

    Citation: Neural Development 2010 5:13

    Content type: Research article

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  23. Photoreceptors of the retina are highly compartmentalized cells that function as the primary sensory neurons for receiving and initiating transmission of visual information. Proper morphogenesis of photorecept...

    Authors: Christine Insinna, Lisa M Baye, Adam Amsterdam, Joseph C Besharse and Brian A Link

    Citation: Neural Development 2010 5:12

    Content type: Research article

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  24. In the adult nervous system, GABA acts as a major inhibitory neurotransmitter; however, at early stages of neurodevelopment, GABA receptor activation leads to membrane depolarization and accumulation of [Ca2+]i. ...

    Authors: Yone J Yoon, Alexander P Gokin and Miguel Martin-Caraballo

    Citation: Neural Development 2010 5:11

    Content type: Research article

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  25. The metatherian Monodelphis domestica, commonly known as the South-American short-tailed opossum, is an appealing animal model for developmental studies on cortico-cerebral development. Given its phylogenetic pos...

    Authors: Elisa Puzzolo and Antonello Mallamaci

    Citation: Neural Development 2010 5:8

    Content type: Research article

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  26. All-trans retinoic acid (atRA) is required for nervous system development, including the developing hindbrain region. Neuron navigator 2 (Nav2) was first identified as an atRA-responsive gene in human neuroblasto...

    Authors: Elizabeth M McNeill, Kenneth P Roos, Dieder Moechars and Margaret Clagett-Dame

    Citation: Neural Development 2010 5:6

    Content type: Research article

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  27. The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes;...

    Authors: Iain M Dykes, Jason Lanier, S Raisa Eng and Eric E Turner

    Citation: Neural Development 2010 5:3

    Content type: Research Article

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  28. Imbalances in the regulation of pro-inflammatory cytokines have been increasingly correlated with a number of severe and prevalent neurodevelopmental disorders, including autism spectrum disorder, schizophreni...

    Authors: Ryan H Lee, Elizabeth A Mills, Neil Schwartz, Mark R Bell, Katherine E Deeg, Edward S Ruthazer, Nicholas Marsh-Armstrong and Carlos D Aizenman

    Citation: Neural Development 2010 5:2

    Content type: Research Article

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  29. The neural crest is a unique population of cells that arise in the vertebrate ectoderm at the neural plate border after which they migrate extensively throughout the embryo, giving rise to a wide range of deri...

    Authors: Alexandra D Almeida, Helen M Wise, Christopher J Hindley, Michael K Slevin, Rebecca S Hartley and Anna Philpott

    Citation: Neural Development 2010 5:1

    Content type: Research article

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  30. Specific dorsomedial (DM) neuroblast lineages of the Drosophila brain amplify their proliferation through generation of transit amplifying intermediate progenitor cells. Together, these DM neuroblast lineages com...

    Authors: Natalya Izergina, Jasmin Balmer, Bruno Bello and Heinrich Reichert

    Citation: Neural Development 2009 4:44

    Content type: Research article

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  31. Agenesis of the corpus callosum is associated with many human developmental syndromes. Key mechanisms regulating callosal formation include the guidance of axons arising from pioneering neurons in the cingulat...

    Authors: Michael Piper, Randal X Moldrich, Charlotta Lindwall, Erica Little, Guy Barry, Sharon Mason, Nana Sunn, Nyoman Dana Kurniawan, Richard M Gronostajski and Linda J Richards

    Citation: Neural Development 2009 4:43

    Content type: Research article

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  32. Gamma motor neurons (γ-MNs) selectively innervate muscle spindle intrafusal fibers and regulate their sensitivity to stretch. They constitute a distinct subpopulation that differs in morphology, physiology and...

    Authors: Neil A Shneider, Meghan N Brown, Courtney A Smith, James Pickel and Francisco J Alvarez

    Citation: Neural Development 2009 4:42

    Content type: Research article

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  33. The Wnt signaling pathway regulates several fundamental developmental processes and recently has been shown to be involved in different aspects of synaptic differentiation and plasticity. Some Wnt signaling compo...

    Authors: Lorena Varela-Nallar, Catalina P Grabowski, Iván E Alfaro, Alejandra R Alvarez and Nibaldo C Inestrosa

    Citation: Neural Development 2009 4:41

    Content type: Research article

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  34. Glutamatergic neurons of the murine cerebral cortex are generated within periventricular proliferative layers of the embryonic pallium, directly from apical precursors or indirectly via their basal progenies. ...

    Authors: Nicola Antonio Maiorano and Antonello Mallamaci

    Citation: Neural Development 2009 4:40

    Content type: Research article

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  35. During the development of the central nervous system (CNS) of Drosophila, neuronal stem cells, the neuroblasts (NBs), first generate a set of highly diverse neurons, the primary neurons that mature to control lar...

    Authors: Baohua Zhou, Darren W Williams, Janet Altman, Lynn M Riddiford and James W Truman

    Citation: Neural Development 2009 4:39

    Content type: Research article

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  36. While many molecules involved in axon guidance have been identified, the cellular and molecular mechanisms by which these molecules regulate growth cone morphology during axon outgrowth remain to be elucidated...

    Authors: Adam D Norris, Jamie O Dyer and Erik A Lundquist

    Citation: Neural Development 2009 4:38

    Content type: Research article

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  37. For the establishment of functional neural circuits that support a wide range of animal behaviors, initial circuits formed in early development have to be reorganized. One way to achieve this is local remodeli...

    Authors: Kohei Shimono, Azusa Fujimoto, Taiichi Tsuyama, Misato Yamamoto-Kochi, Motohiko Sato, Yukako Hattori, Kaoru Sugimura, Tadao Usui, Ken-ichi Kimura and Tadashi Uemura

    Citation: Neural Development 2009 4:37

    Content type: Research article

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  38. Wnt signalling regulates multiple aspects of brain development in vertebrate embryos. A large number of Wnts are expressed in the embryonic forebrain; however, it is poorly understood which specific Wnt performs ...

    Authors: Robyn Quinlan, Manuela Graf, Ivor Mason, Andrew Lumsden and Clemens Kiecker

    Citation: Neural Development 2009 4:35

    Content type: Research article

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  39. Cell surface heparan sulfate proteoglycans (HSPGs) act as co-receptors for multiple families of growth factors that regulate animal cell proliferation, differentiation and patterning. Elimination of heparan su...

    Authors: Yi-Huei Linda Jen, Michele Musacchio and Arthur D Lander

    Citation: Neural Development 2009 4:33

    Content type: Research article

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Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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