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  1. During rat development, histamine (HA) is one of the first neuroactive molecules to appear in the brain, reaching its maximal value at embryonic day 14, a period when neurogenesis of deep layers is occurring i...

    Authors: Anayansi Molina-Hernández, Griselda Rodríguez-Martínez, Itzel Escobedo-Ávila and Iván Velasco
    Citation: Neural Development 2013 8:4
  2. Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as intern...

    Authors: Rebecca Schmidt, Uwe Strähle and Steffen Scholpp
    Citation: Neural Development 2013 8:3
  3. Studies of developmental plasticity may provide insight into plasticity during adulthood, when neural circuitry is less responsive to losses or changes in input. In the mammalian auditory brainstem, globular b...

    Authors: Paul A Nakamura and Karina S Cramer
    Citation: Neural Development 2013 8:2
  4. The homeobox containing transcription factor Uncx4.1 is, amongst others, expressed in the mouse midbrain. The early expression of this transcription factor in the mouse, as well as in the chick midbrain, point...

    Authors: Tamara I Rabe, Gundula Griesel, Stephen Blanke, Andreas Kispert, Michael Leitges, Bert van der Zwaag, J Peter H Burbach, Frédérique Varoqueaux and Ahmed Mansouri
    Citation: Neural Development 2012 7:39
  5. During development, excess synapses form between the central and peripheral nervous systems that are then eliminated to achieve correct connectivity. In the peripheral auditory system, the developing type I sp...

    Authors: Lin-Chien Huang, Meagan Barclay, Kevin Lee, Saša Peter, Gary D Housley, Peter R Thorne and Johanna M Montgomery
    Citation: Neural Development 2012 7:38
  6. Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination. Signal transduction appears to be mediat...

    Authors: Melissa M Langworthy and Bruce Appel
    Citation: Neural Development 2012 7:37
  7. Axons navigate to their future synaptic targets with the help of choice points, intermediate targets that express axon guidance cues. Once they reach a choice point, axons need to switch their response from at...

    Authors: Melanie Philipp, Vera Niederkofler, Marc Debrunner, Tobias Alther, Beat Kunz and Esther T Stoeckli
    Citation: Neural Development 2012 7:36
  8. Precise matching between motoneuron subtypes and the muscles they innervate is a prerequisite for normal behavior. Motoneuron subtype identity is specified by the combination of transcription factors expressed...

    Authors: Steve D Seredick, Liesl Van Ryswyk, Sarah A Hutchinson and Judith S Eisen
    Citation: Neural Development 2012 7:35
  9. Drosophila neurons have dendrites that contain minus-end-out microtubules. This microtubule arrangement is different from that of cultured mammalian neurons, which have mixed polarity microtubules in dendrites.

    Authors: Sarah E Hill, Manpreet Parmar, Kyle W Gheres, Michelle A Guignet, Yanmei Huang, F Rob Jackson and Melissa M Rolls
    Citation: Neural Development 2012 7:34
  10. Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique midkine gene in mammals has two paralogs in zebrafish: midkine-a (mdka) and midkine-b (mdkb). In the z...

    Authors: Jing Luo, Rosa A Uribe, Sarah Hayton, Anda-Alexandra Calinescu, Jeffrey M Gross and Peter F Hitchcock
    Citation: Neural Development 2012 7:33
  11. Although the mechanisms underlying brain patterning and regionalization are very much conserved, the morphology of different brain regions is extraordinarily variable across vertebrate phylogeny. This is espec...

    Authors: Mónica Folgueira, Philippa Bayley, Pavla Navratilova, Thomas S Becker, Stephen W Wilson and Jonathan DW Clarke
    Citation: Neural Development 2012 7:212

    The Erratum to this article has been published in Neural Development 2015 10:22

  12. In holometabolous insects such as Drosophila melanogaster, neuroblasts produce an initial population of diverse neurons during embryogenesis and a much larger set of adult-specific neurons during larval life. In ...

    Authors: Elizabeth C Marin, Katie E Dry, Danielle R Alaimo, Kirstin T Rudd, Anthony R Cillo, Michael E Clenshaw, Nicolas Negre, Kevin P White and James W Truman
    Citation: Neural Development 2012 7:31
  13. The zebrafish retina maintains two populations of stem cells: first, the germinal zone or ciliary marginal zone (CMZ) contains multipotent retinal progenitors that add cells to the retinal periphery as the fis...

    Authors: Jason R Meyers, Lily Hu, Ariel Moses, Kavon Kaboli, Annemarie Papandrea and Pamela A Raymond
    Citation: Neural Development 2012 7:30
  14. Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regene...

    Authors: Caghan Kizil, Stefanie Dudczig, Nikos Kyritsis, Anja Machate, Juliane Blaesche, Volker Kroehne and Michael Brand
    Citation: Neural Development 2012 7:27
  15. Recent findings have indicated the presence of a progenitor domain at the marginal zone/layer 1 of the cerebral cortex, and it has been suggested that these progenitors have neurogenic and gliogenic potential....

    Authors: Joshua J Breunig, David Gate, Rachelle Levy, Javier Rodriguez Jr, Gi Bum Kim, Moise Danielpour, Clive N Svendsen and Terrence Town
    Citation: Neural Development 2012 7:26
  16. The secreted ligand Reelin is believed to regulate the translocation of prospective layer 6 (L6) neocortical neurons into the preplate, a loose layer of pioneer neurons that overlies the ventricular zone. Rece...

    Authors: Ryan S O’Dell, Candida J M Ustine, David A Cameron, Sean M Lawless, Rebecca M Williams, Warren R Zipfel and Eric C Olson
    Citation: Neural Development 2012 7:25
  17. Pannexin 1 forms ion and metabolite permeable hexameric channels and is abundantly expressed in the brain. After discovering pannexin 1 expression in postnatal neural stem and progenitor cells we sought to elu...

    Authors: Leigh E Wicki-Stordeur, Adrian D Dzugalo, Rose M Swansburg, Jocelyne M Suits and Leigh Anne Swayne
    Citation: Neural Development 2012 7:11
  18. The pre B-cell leukemia transcription factor 1 (Pbx1) genes belong to the three amino acid loop extension family of homeodomain proteins that form hetero-oligomeric complexes with other homeodomain transcription ...

    Authors: Paola Sgadò, Elisabetta Ferretti, Daniel Grbec, Yuri Bozzi and Horst H Simon
    Citation: Neural Development 2012 7:24
  19. The sensory neurons and glia of the dorsal root ganglia (DRG) arise from neural crest cells in the developing vertebrate embryo. In mouse and chick, DRG formation is completed during embryogenesis. In contrast...

    Authors: Hillary Faye McGraw, Corey D Snelson, Andrew Prendergast, Arminda Suli and David W Raible
    Citation: Neural Development 2012 7:23
  20. During neocortical development, multiple voltage- and ligand-gated ion channels are differentially expressed in neurons thereby shaping their intrinsic electrical properties. One of these voltage-gated ion cha...

    Authors: Arne Battefeld, Nino Rocha, Konstantin Stadler, Anja U Bräuer and Ulf Strauss
    Citation: Neural Development 2012 7:21
  21. Sulfated glycosaminoglycan chains are known for their regulatory functions during neural development and regeneration. However, it is still unknown whether the sulfate residues alone influence, for example, ne...

    Authors: Michael Karus, Samira Samtleben, Claudia Busse, Teresa Tsai, Irmgard D Dietzel, Andreas Faissner and Stefan Wiese
    Citation: Neural Development 2012 7:20
  22. Understanding the cellular mechanisms regulating axon degeneration and regeneration is crucial for developing treatments for nerve injury and neurodegenerative disease. In neurons, axon degeneration is distinc...

    Authors: Rosario Villegas, Seanna M Martin, Kelley C O’Donnell, Simon A Carrillo, Alvaro Sagasti and Miguel L Allende
    Citation: Neural Development 2012 7:19
  23. Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While midline crossing is achieved through coordinated signaling of attractive and repulsiv...

    Authors: Jennifer Bonner, Michael Letko, Oliver Brant Nikolaus, Lisa Krug, Alexandria Cooper, Benjamin Chadwick, Phoebe Conklin, Amy Lim, Chi-Bin Chien and Richard I Dorsky
    Citation: Neural Development 2012 7:18
  24. The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant re...

    Authors: Thomas K Knott, Pasil A Madany, Ashley A Faden, Mei Xu, Jörg Strotmann, Timothy R Henion and Gerald A Schwarting
    Citation: Neural Development 2012 7:17
  25. In Drosophila, most neurogenetic research is carried out in vivo. Mammalian research demonstrates that primary cell culture techniques provide a powerful model to address cell autonomous and non-autonomous proces...

    Authors: Manuela M Moraru, Boris Egger, Diarra B Bao and Simon G Sprecher
    Citation: Neural Development 2012 7:14
  26. In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus) can regenerate their spinal cord after injury. However, the cellular and molecular mechanis...

    Authors: Marcia Gaete, Rosana Muñoz, Natalia Sánchez, Ricardo Tampe, Mauricio Moreno, Esteban G Contreras, Dasfne Lee-Liu and Juan Larraín
    Citation: Neural Development 2012 7:13

    The Related Article to this article has been published in Nature Protocols 2017 12:nprot.2016.177

  27. A fundamental requirement for development of diverse brain regions is the function of local organizers at morphological boundaries. These organizers are restricted groups of cells that secrete signaling molecu...

    Authors: Benjamin Mattes, Sabrina Weber, João Peres, Qing Chen, Gary Davidson, Corinne Houart and Steffen Scholpp
    Citation: Neural Development 2012 7:12
  28. Cortical GABAergic interneurons (INs) are generated in the medial ganglionic eminence (MGE) and migrate tangentially into cortex. Because most, if not all, migrating MGE-derived INs express the neuregulin (NRG...

    Authors: Hao Li, Shen-Ju Chou, Tadashi Hamasaki, Carlos G Perez-Garcia and Dennis DM O'Leary
    Citation: Neural Development 2012 7:10
  29. The assembly of neural circuits requires the concerted action of both genetically determined and activity-dependent mechanisms. Calcium-regulated transcription may link these processes, but the influence of sp...

    Authors: Scott A Wilke, Benjamin J Hall, Joseph K Antonios, Laura A DeNardo, Stefanie Otto, Bo Yuan, Fading Chen, Elissa M Robbins, Katie Tiglio, Megan E Williams, Zilong Qiu, Thomas Biederer and Anirvan Ghosh
    Citation: Neural Development 2012 7:9
  30. The sequestration of Muscleblind splicing regulators results in myotonic dystrophy. Previous work on Muscleblind has largely focused on its roles in muscle development and maintenance due to the skeletal and c...

    Authors: Kerri A Spilker, George J Wang, Madina S Tugizova and Kang Shen
    Citation: Neural Development 2012 7:7
  31. Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans in embryonic neural environments suggests that ma...

    Authors: Jessica CF Kwok, Ying-Lai Yuen, Wai-Kit Lau, Fu-Xing Zhang, James W Fawcett, Ying-Shing Chan and Daisy KY Shum
    Citation: Neural Development 2012 7:6
  32. The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death. Recently, novel neural stem cells that amplify neural proliferation thr...

    Authors: Yanrui Jiang and Heinrich Reichert
    Citation: Neural Development 2012 7:3
  33. Tangential migration presents the primary mode of migration of cortical interneurons translocating into the cerebral cortex from subpallial domains. This migration takes place in multiple streams with the most...

    Authors: Konstantinos Zarbalis, Youngshik Choe, Julie A Siegenthaler, Lori A Orosco and Samuel J Pleasure
    Citation: Neural Development 2012 7:2
  34. In the decapod crustacean brain, neurogenesis persists throughout the animal's life. After embryogenesis, the central olfactory pathway integrates newborn olfactory local and projection interneurons that repla...

    Authors: Silvia Sintoni, Jeanne L Benton, Barbara S Beltz, Bill S Hansson and Steffen Harzsch
    Citation: Neural Development 2012 7:1
  35. Various members of the family of BTB/POZ zinc-finger transcription factors influence patterns of dendritic branching. One such member, Broad, is notable because its BrZ3 isoform is widely expressed in Drosophila ...

    Authors: Janet A Scott, Darren W Williams and James W Truman
    Citation: Neural Development 2011 6:39
  36. The phylogenetically conserved transcription factor Lola is essential for many aspects of axon growth and guidance, synapse formation and neural circuit development in Drosophila. To date it has been difficult, h...

    Authors: Michael A Gates, Ramakrishnan Kannan and Edward Giniger
    Citation: Neural Development 2011 6:37
  37. Bone morphogenetic protein (BMP)7 evokes both inductive and axon orienting responses in dorsal interneurons (dI neurons) in the developing spinal cord. These events occur sequentially during the development of...

    Authors: Jeanette C Perron and Jane Dodd
    Citation: Neural Development 2011 6:36
  38. The size and cell number of each brain region are influenced by the organization and behavior of neural progenitor cells during embryonic development. Recent studies on developing neocortex have revealed the p...

    Authors: Lynn Wang, Krista K Bluske, Lauren K Dickel and Yasushi Nakagawa
    Citation: Neural Development 2011 6:35
  39. The dopaminergic (DA) neurons present in the central brain of the Drosophila larva are spatially arranged in stereotyped groups that define clusters of bilaterally symmetrical neurons. These clusters have been cl...

    Authors: Jorge Blanco, Rahul Pandey, Martin Wasser and Gerald Udolph
    Citation: Neural Development 2011 6:34
  40. The mechanisms that consolidate neural circuitry are a major focus of neuroscience. In the mammalian cochlea, the refinement of spiral ganglion neuron (SGN) innervation to the inner hair cells (by type I SGNs)...

    Authors: Meagan Barclay, Allen F Ryan and Gary D Housley
    Citation: Neural Development 2011 6:33

Editor-in-Chief

Chris Doe
University of Oregon, USA

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