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  1. Content type: Research article

    Neural stem cell (NSC) differentiation is a complex multistep process that persists in specific regions of the postnatal forebrain and requires tight regulation throughout life. The transcriptional control of ...

    Authors: Bruno Fischer, Kasum Azim, Anahí Hurtado-Chong, Sandra Ramelli, María Fernández and Olivier Raineteau

    Citation: Neural Development 2014 9:23

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  2. Content type: Research article

    Peripheral nerve injuries can severely affect the way that animals perceive signals from the surrounding environment. While damage to peripheral axons generally has a better outcome than injuries to central ne...

    Authors: Maria Laura Ceci, Camila Mardones-Krsulovic, Mario Sánchez, Leonardo E Valdivia and Miguel L Allende

    Citation: Neural Development 2014 9:22

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  3. Content type: Research article

    Neurotrophin-4 (NT-4) and brain derived neurotrophic factor (BDNF) bind to the same receptor, Ntrk2/TrkB, but play distinct roles in the development of the rodent gustatory system. However, the mechanisms unde...

    Authors: Juraj Koudelka, Jacqueline M Horn, Chinnavuth Vatanashevanopakorn and Liliana Minichiello

    Citation: Neural Development 2014 9:21

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  7. Content type: Research article

    Longitudinal axons grow parallel to the embryonic midline to connect distant regions of the central nervous system. Previous studies suggested that repulsive midline signals guide pioneer longitudinal axons by...

    Authors: Minkyung Kim, W Todd Farmer, Brielle Bjorke, Samuel A McMahon, Pierre J Fabre, Frédéric Charron and Grant S Mastick

    Citation: Neural Development 2014 9:17

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  8. Content type: Research Article

    Mouse visual thalamus has emerged as a powerful model for understanding the mechanisms underlying neural circuit formation and function. Three distinct nuclei within mouse thalamus receive retinal input, the d...

    Authors: Sarah Hammer, Gabriela L Carrillo, Gubbi Govindaiah, Aboozar Monavarfeshani, Joseph S Bircher, Jianmin Su, William Guido and Michael A Fox

    Citation: Neural Development 2014 9:16

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  9. Content type: Research Article

    Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) regulate the survival of gustatory neurons, axon growth and branching, and innervation of taste buds during development. These actions are larg...

    Authors: Da Fei, Tao Huang and Robin F Krimm

    Citation: Neural Development 2014 9:15

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  12. Content type: Research article

    Xenopus laevis has regenerative and non-regenerative stages. As a tadpole, it is fully capable of functional recovery after a spinal cord injury, while its juvenile form (froglet) loses this capability during met...

    Authors: Dasfne Lee-Liu, Mauricio Moreno, Leonardo I Almonacid, Víctor S Tapia, Rosana Muñoz, Javier von Marées, Marcia Gaete, Francisco Melo and Juan Larraín

    Citation: Neural Development 2014 9:12

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  13. Content type: Research article

    Proper binocular vision depends on the routing at the optic chiasm of the correct proportion of retinal ganglion cell (RGC) axons that project to the same (ipsilateral) and opposite (contralateral) side of the...

    Authors: Punita Bhansali, Ilana Rayport, Alexandra Rebsam and Carol Mason

    Citation: Neural Development 2014 9:11

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  15. Content type: Research article

    As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b. The shared presence of four specific amino acid motifs—M1 to M4—in the N-terminal region of mamm...

    Authors: Alejandro Pinzón-Olejua, Cornelia Welte, Houari Abdesselem, Edward Málaga-Trillo and Claudia AO Stuermer

    Citation: Neural Development 2014 9:8

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  16. Content type: Research article

    Morphogenesis of the zebrafish neural tube requires the coordinated movement of many cells in both time and space. A good example of this is the movement of the cells in the zebrafish neural plate as they conv...

    Authors: Claudio Araya, Marcel Tawk, Gemma C Girdler, Marta Costa, Carlos Carmona-Fontaine and Jonathan DW Clarke

    Citation: Neural Development 2014 9:9

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  17. Content type: Research article

    Latrophilins (LPHNs) are a small family of neuronal adhesion-GPCRs originally discovered as receptors for the black widow spider toxin α-latrotoxin. Mutations in LPHN3 have recently been identified as risk factor...

    Authors: Matthew L O’Sullivan, Francesca Martini, Sventja von Daake, Davide Comoletti and Anirvan Ghosh

    Citation: Neural Development 2014 9:7

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  18. Content type: Research article

    The genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poor...

    Authors: Matthew J Eckler, Kathryn A Larkin, William L McKenna, Sol Katzman, Chao Guo, Robin Roque, Axel Visel, John L L Rubenstein and Bin Chen

    Citation: Neural Development 2014 9:6

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  19. Content type: Research article

    Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is req...

    Authors: Biliana O Veleva-Rotse, James L Smart, Annette F Baas, Benjamin Edmonds, Zi-ming Zhao, Allyson Brown, Lillian R Klug, Kelly Hansen, Gabrielle Reilly, Alexandria P Gardner, Krishnaveni Subbiah, Eric A Gaucher, Hans Clevers and Anthony P Barnes

    Citation: Neural Development 2014 9:5

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  20. Content type: Research article

    Vertebrates and invertebrates obtain visual motion information by channeling moving visual cues perceived by the retina through specific motion sensitive synaptic relays in the brain. In Drosophila, the series of...

    Authors: Carlos Oliva, Ching-Man Choi, Laura J J Nicolai, Natalia Mora, Natalie De Geest and Bassem A Hassan

    Citation: Neural Development 2014 9:4

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  22. Content type: Research article

    There are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene. This functional specificity is derived from distinct RGC ...

    Authors: Jason W Triplett, Wei Wei, Cristina Gonzalez, Neal T Sweeney, Andrew D Huberman, Marla B Feller and David A Feldheim

    Citation: Neural Development 2014 9:2

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  23. Content type: Research article

    The functional integration of the cerebellum into a number of different neural systems is governed by the connection of its output axons. In amniotes, the majority of this output is mediated by an evolutionari...

    Authors: Mary J Green and Richard JT Wingate

    Citation: Neural Development 2014 9:1

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  24. Content type: Research article

    The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. It is well known ...

    Authors: Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé

    Citation: Neural Development 2013 8:25

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  25. Content type: Short Report

    The dorsal lateral geniculate nucleus (dLGN) of the mouse thalamus has emerged as a powerful experimental system for understanding the refinement of developing sensory connections. Interestingly, many of the b...

    Authors: Tania A Seabrook, Thomas E Krahe, Gubbi Govindaiah and William Guido

    Citation: Neural Development 2013 8:24

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  26. Content type: Meeting report

    During the EMBO course ‘Imaging of Neural Development in Zebrafish’, held on September 9–15th 2013, researchers from different backgrounds shared their latest results, ideas and practical expertise on zebrafish a...

    Authors: Steffen Scholpp, Lucia Poggi and Mihaela Žigman

    Citation: Neural Development 2013 8:23

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  27. Content type: Research article

    Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution assays have established that the XMAP215/Dis1/TOG family of MT regulators function as MT ‘plus-e...

    Authors: Laura Anne Lowery, Alina Stout, Anna E Faris, Liya Ding, Michelle A Baird, Michael W Davidson, Gaudenz Danuser and David Van Vactor

    Citation: Neural Development 2013 8:22

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  29. Content type: Research Article

    Hearing depends on correct functioning of the cochlear hair cells, and their innervation by spiral ganglion neurons. Most of the insight into the embryological and molecular development of this sensory system ...

    Authors: Heiko Locher, Johan HM Frijns, Liesbeth van Iperen, John CMJ de Groot, Margriet A Huisman and Susana M Chuva de Sousa Lopes

    Citation: Neural Development 2013 8:20

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  30. Content type: Research Article

    The conserved habenular neural circuit relays cognitive information from the forebrain into the ventral mid- and hindbrain. In zebrafish, the bilaterally formed habenulae in the dorsal diencephalon are made up...

    Authors: Carlo A Beretta, Nicolas Dross, Peter Bankhead and Matthias Carl

    Citation: Neural Development 2013 8:19

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  31. Content type: Research Article

    Circuit formation in the nervous system essentially relies on the proper development of neurons and their processes. In this context, the ubiquitin ligase Nedd4 is a crucial modulator of axonal and dendritic b...

    Authors: Michael J Schmeisser, Susanne J Kühl, Michael Schoen, Nathalie H Beth, Tobias M Weis, Andreas M Grabrucker, Michael Kühl and Tobias M Boeckers

    Citation: Neural Development 2013 8:18

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  33. Content type: Research Article

    Neurons in sympathetic ganglia and neuroendocrine cells in the adrenal medulla share not only their embryonic origin from sympathoadrenal precursors in the neural crest but also a range of functional features....

    Authors: Jutta Stubbusch, Priyanka Narasimhan, Katrin Huber, Klaus Unsicker, Hermann Rohrer and Uwe Ernsberger

    Citation: Neural Development 2013 8:16

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  34. Content type: Research article

    Spinal commissural axons represent a model system for deciphering the molecular logic that regulates the guidance of midline-crossing axons in the developing central nervous system (CNS). Whether the same or s...

    Authors: Tracy S Tran, Edward Carlin, Ruihe Lin, Edward Martinez, Jane E Johnson and Zaven Kaprielian

    Citation: Neural Development 2013 8:15

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  35. Content type: Research article

    During cerebral cortex development, multipotent neural progenitor cells generate a variety of neuronal subtypes in a fixed temporal order. How a single neural progenitor cell generates the diversity of cortica...

    Authors: Nathalie Saurat, Therese Andersson, Navneet A Vasistha, Zoltan Molnar and Frederick J Livesey

    Citation: Neural Development 2013 8:14

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  36. Content type: Research article

    In order to fulfill their chemosensory function, olfactory neurons are in direct contact with the external environment and are therefore exposed to environmental aggressive factors. Olfaction is maintained thr...

    Authors: Marie Paschaki, Laura Cammas, Yuko Muta, Yoko Matsuoka, Siu-Shan Mak, Monika Rataj-Baniowska, Valurie Fraulob, Pascal Dolle and Raj K Ladher

    Citation: Neural Development 2013 8:13

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  37. Content type: Research article

    The neural crest (NC) is a transient embryonic structure unique to vertebrates, which generates peripheral sensory and autonomic neurons, glia, neuroendocrine chromaffin and thyroid C-cells, melanocytes, and m...

    Authors: Stella Shtukmaster, Marie Catherine Schier, Katrin Huber, Shlomo Krispin, Chaya Kalcheim and Klaus Unsicker

    Citation: Neural Development 2013 8:12

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  39. Content type: Research article

    The conserved Caenorhabditis elegans proteins NID-1/nidogen and PTP-3A/LAR-RPTP function to efficiently localize the presynaptic scaffold protein SYD-2/α-liprin at active zones. Loss of function in these molecule...

    Authors: Raymond C Caylor, Yishi Jin and Brian D Ackley

    Citation: Neural Development 2013 8:10

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  40. Content type: Research article

    Teleost fish display widespread post-embryonic neurogenesis originating from many different proliferative niches that are distributed along the brain axis. During the development of the central nervous system ...

    Authors: Jan Kaslin, Volker Kroehne, Francesca Benato, Francesco Argenton and Michael Brand

    Citation: Neural Development 2013 8:9

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  42. Content type: Research article

    During cerebral cortical development, neural precursor-precursor interactions in the ventricular zone neurogenic niche coordinate signaling pathways that regulate proliferation and differentiation. Previous st...

    Authors: Jianing Zhang, Julie R Shemezis, Erin R McQuinn, Jing Wang, Maria Sverdlov and Anjen Chenn

    Citation: Neural Development 2013 8:7

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  43. Content type: Research article

    The central complex is a multimodal information-processing center in the insect brain composed of thousands of neurons representing more than 50 neural types arranged in a stereotyped modular neuroarchitecture...

    Authors: Nadia Riebli, Gudrun Viktorin and Heinrich Reichert

    Citation: Neural Development 2013 8:6

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  44. Content type: Research article

    Morphogenesis requires developmental processes to occur both at the right time and in the right place. During neural tube formation in the zebrafish embryo, the generation of the apical specializations of the ...

    Authors: Gemma C Girdler, Claudio Araya, Xiaoyun Ren and Jonathan DW Clarke

    Citation: Neural Development 2013 8:5

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  45. Content type: Research article

    During rat development, histamine (HA) is one of the first neuroactive molecules to appear in the brain, reaching its maximal value at embryonic day 14, a period when neurogenesis of deep layers is occurring i...

    Authors: Anayansi Molina-Hernández, Griselda Rodríguez-Martínez, Itzel Escobedo-Ávila and Iván Velasco

    Citation: Neural Development 2013 8:4

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  46. Content type: Review

    Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as intern...

    Authors: Rebecca Schmidt, Uwe Strähle and Steffen Scholpp

    Citation: Neural Development 2013 8:3

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  47. Content type: Research article

    Studies of developmental plasticity may provide insight into plasticity during adulthood, when neural circuitry is less responsive to losses or changes in input. In the mammalian auditory brainstem, globular b...

    Authors: Paul A Nakamura and Karina S Cramer

    Citation: Neural Development 2013 8:2

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  49. Content type: Research article

    The homeobox containing transcription factor Uncx4.1 is, amongst others, expressed in the mouse midbrain. The early expression of this transcription factor in the mouse, as well as in the chick midbrain, point...

    Authors: Tamara I Rabe, Gundula Griesel, Stephen Blanke, Andreas Kispert, Michael Leitges, Bert van der Zwaag, J Peter H Burbach, Frédérique Varoqueaux and Ahmed Mansouri

    Citation: Neural Development 2012 7:39

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  50. Content type: Research article

    During development, excess synapses form between the central and peripheral nervous systems that are then eliminated to achieve correct connectivity. In the peripheral auditory system, the developing type I sp...

    Authors: Lin-Chien Huang, Meagan Barclay, Kevin Lee, Saša Peter, Gary D Housley, Peter R Thorne and Johanna M Montgomery

    Citation: Neural Development 2012 7:38

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Editors-in-Chief

Chris Doe
University of Oregon, USA
William Harris
University of Cambridge, UK
Kang Shen
Stanford University, USA
Rachel Wong
University of Washington, USA

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Neural Development

ISSN: 1749-8104