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  2. More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed fundamental insights into our understanding of axon guidance mechanisms, neural differentiation, and early cell fate decisions...

    Authors: Matthew Q. Clark, Aref Arzan Zarin, Arnaldo Carreira-Rosario and Chris Q. Doe

    Citation: Neural Development 2018 13:6

    Content type: Review

    Published on:

  3. Brain function requires precise neural circuit assembly during development. Establishing a functional circuit involves multiple coordinated steps ranging from neural cell fate specification to proper matching ...

    Authors: Hongjie Li, S. Andrew Shuster, Jiefu Li and Liqun Luo

    Citation: Neural Development 2018 13:5

    Content type: Review

    Published on:

  4. Activity in neurons drives afferent competition that is critical for the refinement of nascent neural circuits. In ferrets, when an eye is lost in early development, surviving retinogeniculate afferents from t...

    Authors: Samuel Wilson Failor, Arash Ng and Hwai-Jong Cheng

    Citation: Neural Development 2018 13:4

    Content type: Research article

    Published on:

  5. Most oligodendrocytes of the spinal cord originate from ventral progenitor cells of the pMN domain, characterized by expression of the transcription factor Olig2. A minority of oligodendrocytes is also recogni...

    Authors: Marie-Amélie Farreny, Eric Agius, Sophie Bel-Vialar, Nathalie Escalas, Nagham Khouri-Farah, Chadi Soukkarieh, Cathy Danesin, Fabienne Pituello, Philippe Cochard and Cathy Soula

    Citation: Neural Development 2018 13:3

    Content type: Research article

    Published on:

  6. Radial glial stem cells within the developing nervous system generate a variety of post-mitotic cells, including neurons and glial cells, as well as the specialised multi-ciliated cells that line the walls of ...

    Authors: Diana Vidovic, Raul Ayala Davila, Richard M. Gronostajski, Tracey J. Harvey and Michael Piper

    Citation: Neural Development 2018 13:2

    Content type: Short Report

    Published on:

  7. After publication of the original article [1] it was realised that there were errors in figures 2a,b,f,g, which arose as a result of preparing figures from data collected and analysed at the same time as the w...

    Authors: Olivier Clément, Isabel Anne Hemming, Ivan Enghian Gladwyn-Ng, Zhengdong Qu, Shan Shan Li, Michael Piper and Julian Ik-Tsen Heng

    Citation: Neural Development 2018 13:1

    Content type: Correction

    Published on:

    The original article was published in Neural Development 2017 12:8

  8. The multiplex, lattice mosaic of cone photoreceptors in the adult fish retina is a compelling example of a highly ordered epithelial cell pattern, with single cell width rows and columns of cones and precisely...

    Authors: Mikiko Nagashima, Jeremy Hadidjojo, Linda K. Barthel, David K. Lubensky and Pamela A. Raymond

    Citation: Neural Development 2017 12:20

    Content type: Research article

    Published on:

  9. Patterning of the telencephalic neuroepithelium is a tightly regulated process controlled by transcription factors and signalling molecules. The cortical primordium is flanked by two signalling centres, the he...

    Authors: Geeta Godbole, Achira Roy, Ashwin S. Shetty and Shubha Tole

    Citation: Neural Development 2017 12:19

    Content type: Short report

    Published on:

  10. The axons of Olfactory Sensory Neurons (OSNs) project to reproducible target locations within the Olfactory Bulb (OB), converting odorant experience into a spatial map of neural activity. We characterized the ...

    Authors: Xin Shao, Vanisha Lakhina, Puneet Dang, Ryan P. Cheng, Christina L. Marcaccio and Jonathan A. Raper

    Citation: Neural Development 2017 12:18

    Content type: Research

    Published on:

  11. Cyclin-dependent kinase (CDK) inhibitors play an important role in regulating cell cycle progression, cell cycle exit and cell differentiation. p27KIP1 (p27), one of the major CDK inhibitors in the retina, has be...

    Authors: Mariko Ogawa, Fuminori Saitoh, Norihiro Sudou, Fumi Sato and Hiroki Fujieda

    Citation: Neural Development 2017 12:17

    Content type: Research article

    Published on:

  12. Amacrine interneurons that modulate synaptic plasticity between bipolar and ganglion cells constitute the most diverse cell type in the retina. Most are inhibitory neurons using either GABA or glycine as neuro...

    Authors: Nathalie Bessodes, Karine Parain, Odile Bronchain, Eric J. Bellefroid and Muriel Perron

    Citation: Neural Development 2017 12:16

    Content type: Research article

    Published on:

  13. After axon severing, neurons recover function by reinitiating axon outgrowth. New outgrowth often originates from the remaining axon stump. However, in many mammalian neurons, new axons initiate from a dendrit...

    Authors: Kavitha S. Rao and Melissa M. Rolls

    Citation: Neural Development 2017 12:15

    Content type: Research

    Published on:

  14. Glutamatergic neurons in the cerebral cortex are derived from embryonic neural stem cells known as radial glial progenitors (RGPs). Early RGPs, present at the onset of cortical neurogenesis, are classically th...

    Authors: E. S. Kaplan, K. A. Ramos-Laguna, A. B. Mihalas, R. A. M. Daza and R. F. Hevner

    Citation: Neural Development 2017 12:14

    Content type: Short report

    Published on:

  15. Olfactory bulb (OB) interneurons are known to represent diverse neuronal subtypes, which are thought to originate from a number of telencephalic regions including the embryonic dorsal lateral ganglionic eminen...

    Authors: Shenyue Qin, Stephanie M. Ware, Ronald R. Waclaw and Kenneth Campbell

    Citation: Neural Development 2017 12:13

    Content type: Research article

    Published on:

  16. Regeneration of neurons in the central nervous system is poor in humans. In other vertebrates neural regeneration does occur efficiently and involves reactivation of developmental processes. Within the neural ...

    Authors: Jeremy Ng Chi Kei, Peter David Currie and Patricia Regina Jusuf

    Citation: Neural Development 2017 12:12

    Content type: Research article

    Published on:

  17. The cells of the mesencephalic trigeminal nucleus (MTN) are the proprioceptive sensory neurons that innervate the jaw closing muscles. These cells differentiate close to the two key signalling centres that inf...

    Authors: Marcela Lipovsek, Julia Ledderose, Thomas Butts, Tanguy Lafont, Clemens Kiecker, Andrea Wizenmann and Anthony Graham

    Citation: Neural Development 2017 12:11

    Content type: Research article

    Published on:

  18. In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on signals that control their specification but also the...

    Authors: Julien Laussu, Christophe Audouard, Anthony Kischel, Poincyane Assis-Nascimento, Nathalie Escalas, Daniel J. Liebl, Cathy Soula and Alice Davy

    Citation: Neural Development 2017 12:10

    Content type: Research article

    Published on:

  19. The corpus callosum forms the major interhemispheric connection in the human brain and is unique to eutherian (or placental) mammals. The developmental events associated with the evolutionary emergence of this...

    Authors: Ilan Gobius, Rodrigo Suárez, Laura Morcom, Annalisa Paolino, Timothy J. Edwards, Peter Kozulin and Linda J. Richards

    Citation: Neural Development 2017 12:9

    Content type: Short Report

    Published on:

  20. During the development of the mammalian cerebral cortex, newborn postmitotic projection neurons are born from local neural stem cells and must undergo radial migration so as to position themselves appropriatel...

    Authors: Olivier Clément, Isabel Anne Hemming, Ivan Enghian Gladwyn-Ng, Zhengdong Qu, Shan Shan Li, Michael Piper and Julian Ik-Tsen Heng

    Citation: Neural Development 2017 12:8

    Content type: Short Report

    Published on:

    The Correction to this article has been published in Neural Development 2018 13:1

  21. In developing tissues, cell polarity and tissue architecture play essential roles in the regulation of proliferation and differentiation. During cerebral cortical development, adherens junctions link highly po...

    Authors: Jennifer Rakotomamonjy, Molly Brunner, Christoph Jüschke, Keling Zang, Eric J. Huang, Louis F. Reichardt and Anjen Chenn

    Citation: Neural Development 2017 12:7

    Content type: Short Report

    Published on:

  22. Sensory processing relies on projections from the thalamus to the neocortex being established during development. Information from different sensory modalities reaching the thalamus is segregated into speciali...

    Authors: Manuela D. Mitsogiannis, Graham E. Little and Kevin J. Mitchell

    Citation: Neural Development 2017 12:6

    Content type: Research article

    Published on:

  23. How neurons change their cytoskeleton to adopt their complex polarized morphology is still not understood. Growing evidence suggests that proteins that help build microtubule structures during cell division ar...

    Authors: Katrina C. McNeely, Timothy D. Cupp, Jessica Neville Little, Kerstin M. Janisch, Ayushma Shrestha and Noelle D. Dwyer

    Citation: Neural Development 2017 12:5

    Content type: Research article

    Published on:

  24. The actin cytoskeleton-associated protein palladin plays an important role in cell motility, morphogenesis and adhesion. In mice, Palladin deficient embryos are lethal before embryonic day (E) 15.5, and exhibi...

    Authors: Juan Tan, Xue-Jiao Chen, Chun-Ling Shen, Hong-Xin Zhang, Ling-Yun Tang, Shun-Yuan Lu, Wen-Ting Wu, Ying Kuang, Jian Fei and Zhu-Gang Wang

    Citation: Neural Development 2017 12:4

    Content type: Research article

    Published on:

  25. Formation of precise neuronal connections requires proper axon guidance. Microtubules (MTs) of the growth cone provide a critical driving force during navigation of the growing ends of axons. Pioneer MTs and t...

    Authors: Burcu Erdogan, Garrett M. Cammarata, Eric J. Lee, Benjamin C. Pratt, Andrew F. Francl, Erin L. Rutherford and Laura Anne Lowery

    Citation: Neural Development 2017 12:3

    Content type: Research article

    Published on:

  26. The mammalian primary olfactory system has a spatially-ordered projection in which olfactory sensory neurons (OSNs) located in the dorsomedial (DM) and ventrolateral (VL) region of the olfactory epithelium (OE...

    Authors: Eerdunfu, Naoki Ihara, Bao Ligao, Yuji Ikegaya and Haruki Takeuchi

    Citation: Neural Development 2017 12:2

    Content type: Short report

    Published on:

  27. Drosophila and mammalian neural progenitors typically generate a diverse family of neurons in a stereotyped order. Neuronal diversity can be generated by the sequential expression of t...

    Authors: Keiko Hirono, Minoree Kohwi, Matt Q. Clark, Ellie S. Heckscher and Chris Q. Doe

    Citation: Neural Development 2017 12:1

    Content type: Research article

    Published on:

  28. Neurons arise in very specific regions of the neural tube, controlled by components of the Notch signalling pathway, proneural genes, and other bHLH transcription factors. How these specific neuronal areas in ...

    Authors: Michelle Ware, Houda Hamdi-Rozé, Julien Le Friec, Véronique David and Valérie Dupé

    Citation: Neural Development 2016 11:22

    Content type: Research Article

    Published on:

  29. The proper spatial and temporal regulation of dorsal telencephalic progenitor behavior is a prerequisite for the formation of the highly-organized, six-layered cerebral cortex. Premature differentiation of cel...

    Authors: Peter J. Bosch, Leah C. Fuller, Carolyn M. Sleeth and Joshua A. Weiner

    Citation: Neural Development 2016 11:21

    Content type: Research article

    Published on:

  30. Although the vast majority of cells in our brains are glia, we are only beginning to understand programs governing their development, especially within the embryonic hypothalamus. In mice, gliogenesis is a pro...

    Authors: Candace M. Marsters, Jessica M. Rosin, Hayley F. Thornton, Shaghayegh Aslanpour, Natasha Klenin, Grey Wilkinson, Carol Schuurmans, Quentin J. Pittman and Deborah M. Kurrasch

    Citation: Neural Development 2016 11:20

    Content type: Research article

    Published on:

  32. Oculomotor neurons develop initially like typical motor neurons, projecting axons out of the ventral midbrain to their ipsilateral targets, the extraocular muscles. However, in all vertebrates, after the oculo...

    Authors: Brielle Bjorke, Farnaz Shoja-Taheri, Minkyung Kim, G. Eric Robinson, Tatiana Fontelonga, Kyung-Tai Kim, Mi-Ryoung Song and Grant S. Mastick

    Citation: Neural Development 2016 11:18

    Content type: Research article

    Published on:

  33. The mouse cerebellum (Cb) has a remarkably complex foliated three-dimensional (3D) structure, but a stereotypical cytoarchitecture and local circuitry. Little is known of the cellular behaviors and genes that ...

    Authors: Emilie Legué, Jackie L. Gottshall, Edouard Jaumouillé, Alberto Roselló-Díez, Wei Shi, Luis Humberto Barraza, Senna Washington, Rachel L. Grant and Alexandra L. Joyner

    Citation: Neural Development 2016 11:17

    Content type: Research article

    Published on:

  34. Alterations in neurotransmitter phenotypes of specific neurons can cause imbalances in excitation and inhibition in the central nervous system (CNS), leading to diseases. Therefore, the correct specification a...

    Authors: William C. Hilinski, Jonathan R. Bostrom, Samantha J. England, José L. Juárez-Morales, Sarah de Jager, Olivier Armant, Jessica Legradi, Uwe Strähle, Brian A. Link and Katharine E. Lewis

    Citation: Neural Development 2016 11:16

    Content type: Research article

    Published on:

  36. Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability. Previous studies have implicated changes in dendritic spine architecture as the primary result of ...

    Authors: Torrey L. S. Truszkowski, Eric J. James, Mashfiq Hasan, Tyler J. Wishard, Zhenyu Liu, Kara G. Pratt, Hollis T. Cline and Carlos D. Aizenman

    Citation: Neural Development 2016 11:14

    Content type: Research article

    Published on:

  37. Recent genetic studies in model organisms, such as Drosophila, C. elegans and mice, have highlighted a critical role for dual leucine zipper kinase (DLK) in neural development and axonal responses to injury. Howe...

    Authors: Andréanne Blondeau, Jean-François Lucier, Dominick Matteau, Lauralyne Dumont, Sébastien Rodrigue, Pierre-Étienne Jacques and Richard Blouin

    Citation: Neural Development 2016 11:13

    Content type: Research article

    Published on:

  38. Neurons in the hypothalamus function to regulate the state of the animal during both learned and innate behaviors, and alterations in hypothalamic development may contribute to pathological conditions such as ...

    Authors: Katie Sokolowski, Tuyen Tran, Shigeyuki Esumi, Yasmin Kamal, Livio Oboti, Julieta Lischinsky, Meredith Goodrich, Andrew Lam, Margaret Carter, Yasushi Nakagawa and Joshua G. Corbin

    Citation: Neural Development 2016 11:12

    Content type: Research article

    Published on:

  39. Autism Spectrum Disorders (ASD) are the second most common developmental cause of disability in the United States. ASDs are accompanied with substantial economic and emotional cost. The brains of ASD patients ...

    Authors: Christine Pérez, Darrell Sawmiller and Jun Tan

    Citation: Neural Development 2016 11:11

    Content type: Review

    Published on:

  40. Retinal ganglion cell (RGC) differentiation in vivo is a highly stereotyped process, likely resulting from the interaction of cell type-specific transcription factors and tissue-derived signaling factors. The ...

    Authors: Paola Lepanto, Camila Davison, Gabriela Casanova, Jose L. Badano and Flavio R. Zolessi

    Citation: Neural Development 2016 11:10

    Content type: Research article

    Published on:

  41. Brain size and patterning are dependent on dosage-sensitive morphogen signaling pathways – yet how these pathways are calibrated remains enigmatic. Recent studies point to a new role for microRNAs in tempering...

    Authors: Giuliana Caronia-Brown, Angela Anderegg and Rajeshwar Awatramani

    Citation: Neural Development 2016 11:9

    Content type: Research article

    Published on:

  43. The development of neural circuits within the embryonic cerebral cortex relies on the timely production of neurons, their positioning within the embryonic cerebral cortex as well as their terminal differentiat...

    Authors: Ivan Gladwyn-Ng, Lieven Huang, Linh Ngo, Shan Shan Li, Zhengdong Qu, Hannah Kate Vanyai, Hayley Daniella Cullen, John Michael Davis and Julian Ik-Tsen Heng

    Citation: Neural Development 2016 11:7

    Content type: Short Report

    Published on:

  44. The editors of Neural Development would like to thank all the reviewers who have contributed to the journal in Volume 10 (2015).

    Authors: Chris Q. Doe, William Harris, Kang Shen and Rachel Wong

    Citation: Neural Development 2016 11:6

    Content type: Reviewer acknowledgement

    Published on:

  45. For neurons to function correctly in neuronal circuitry they must utilize appropriate neurotransmitters. However, even though neurotransmitter specificity is one of the most important and defining properties o...

    Authors: José L. Juárez-Morales, Claus J. Schulte, Sofia A. Pezoa, Grace K. Vallejo, William C. Hilinski, Samantha J. England, Sarah de Jager and Katharine E. Lewis

    Citation: Neural Development 2016 11:5

    Content type: Research article

    Published on:

  46. Nerve growth factor (NGF) is the prototypical target-derived neurotrophic factor required for sympathetic neuron survival and for the growth and ramification of sympathetic axons within most but not all sympat...

    Authors: Gerard W. O’Keeffe, Humberto Gutierrez, Laura Howard, Christopher W. Laurie, Catarina Osorio, Núria Gavaldà, Sean L. Wyatt and Alun M. Davies

    Citation: Neural Development 2016 11:4

    Content type: Research article

    Published on:

  47. The cranial sensory ganglia represent populations of neurons with distinct functions, or sensory modalities. The production of individual ganglia from distinct neurogenic placodes with different developmental ...

    Authors: Cedric Patthey, Harry Clifford, Wilfried Haerty, Chris P. Ponting, Sebastian M. Shimeld and Jo Begbie

    Citation: Neural Development 2016 11:3

    Content type: Research article

    Published on:

  48. Charcot-Marie-Tooth2b (CMT2b) is an axonal form of a human neurodegenerative disease that preferentially affects sensory neurons. CMT2b is dominantly inherited and is characterized by unusually early onset, pr...

    Authors: Olga Y. Ponomareva, Kevin W. Eliceiri and Mary C. Halloran

    Citation: Neural Development 2016 11:2

    Content type: Research article

    Published on:

  49. Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the neural tissue, concomitantly with other morphogenetic changes that contribue to this process. In...

    Authors: Pradeepa Jayachandran, Valerie N. Olmo, Stephanie P. Sanchez, Rebecca J. McFarland, Eudorah Vital, Jonathan M. Werner, Elim Hong, Neus Sanchez-Alberola, Aleksey Molodstov and Rachel M. Brewster

    Citation: Neural Development 2016 11:1

    Content type: Research article

    Published on:

  50. Notch signaling has been conserved throughout evolution and plays a fundamental role in various neural developmental processes and the pathogenesis of several human cancers and genetic disorders. However, how ...

    Authors: Yi-Chuan Cheng, Yin-Cheng Huang, Tu-Hsueh Yeh, Hung-Yu Shih, Ching-Yu Lin, Sheng-Jia Lin, Ching-Chi Chiu, Ching-Wen Huang and Yun-Jin Jiang

    Citation: Neural Development 2015 10:28

    Content type: Research article

    Published on:

Editors-in-Chief

Chris Doe
University of Oregon, USA
Julia Kaltschmidt
Stanford University, USA
Beth Stevens
Harvard University, USA

 

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Neural Development

ISSN: 1749-8104