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Research article
Neurons in the hypothalamus function to regulate the state of the animal during both learned and innate behaviors, and alterations in hypothalamic development may contribute to pathological conditions such as ...
Neural Development 2016 11:12
Published on: 21 May 2016
Review
Autism Spectrum Disorders (ASD) are the second most common developmental cause of disability in the United States. ASDs are accompanied with substantial economic and emotional cost. The brains of ASD patients ...
Neural Development 2016 11:11
Published on: 18 April 2016
Research article
Retinal ganglion cell (RGC) differentiation in vivo is a highly stereotyped process, likely resulting from the interaction of cell type-specific transcription factors and tissue-derived signaling factors. The ...
Neural Development 2016 11:10
Published on: 6 April 2016
Research article
Brain size and patterning are dependent on dosage-sensitive morphogen signaling pathways – yet how these pathways are calibrated remains enigmatic. Recent studies point to a new role for microRNAs in tempering...
Neural Development 2016 11:9
Published on: 5 April 2016
Review
During development, a coordinated and integrated series of events must be accomplished in order to generate functional neural circuits. Axons must navigate toward target cells, build synaptic connections, and ...
Neural Development 2016 11:8
Published on: 23 March 2016
Short Report
The development of neural circuits within the embryonic cerebral cortex relies on the timely production of neurons, their positioning within the embryonic cerebral cortex as well as their terminal differentiat...
Neural Development 2016 11:7
Published on: 11 March 2016
Reviewer acknowledgement
The editors of Neural Development would like to thank all the reviewers who have contributed to the journal in Volume 10 (2015).
Neural Development 2016 11:6
Published on: 8 March 2016
Research article
For neurons to function correctly in neuronal circuitry they must utilize appropriate neurotransmitters. However, even though neurotransmitter specificity is one of the most important and defining properties o...
Neural Development 2016 11:5
Published on: 19 February 2016
Research article
Nerve growth factor (NGF) is the prototypical target-derived neurotrophic factor required for sympathetic neuron survival and for the growth and ramification of sympathetic axons within most but not all sympat...
Neural Development 2016 11:4
Published on: 15 February 2016
Research article
The cranial sensory ganglia represent populations of neurons with distinct functions, or sensory modalities. The production of individual ganglia from distinct neurogenic placodes with different developmental ...
Neural Development 2016 11:3
Published on: 27 January 2016
Research article
Charcot-Marie-Tooth2b (CMT2b) is an axonal form of a human neurodegenerative disease that preferentially affects sensory neurons. CMT2b is dominantly inherited and is characterized by unusually early onset, pr...
Neural Development 2016 11:2
Published on: 20 January 2016
Research article
Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the neural tissue, concomitantly with other morphogenetic changes that contribue to this process. In...
Neural Development 2016 11:1
Published on: 18 January 2016
Research article
Notch signaling has been conserved throughout evolution and plays a fundamental role in various neural developmental processes and the pathogenesis of several human cancers and genetic disorders. However, how ...
Neural Development 2015 10:28
Published on: 30 December 2015
Research article
In the auditory brainstem, ventral cochlear nucleus (VCN) axons project to the contralateral, but not ipsilateral, medial nucleus of trapezoid body (MNTB), terminating in the calyx of Held. Dorsal VCN neurons,...
Neural Development 2015 10:27
Published on: 15 December 2015
Research Article
In mouse embryos, the Pax6 transcription factor is expressed in the progenitors of thalamic neurons but not in thalamic neurons themselves. Its null-mutation causes early mis-patterning of thalamic progenitors...
Neural Development 2015 10:26
Published on: 31 October 2015
Research article
During sensori-motor circuit development, the somas of motoneurons (MN) are distributed in a topographic manner in the ventral horn of the neural tube. Indeed, their position within the lateral motor columns (...
Neural Development 2015 10:25
Published on: 26 October 2015
Review
The embryonic vertebrate neural tube is divided along its dorsoventral (DV) axis into eleven molecularly discrete progenitor domains. Each of these domains gives rise to distinct neuronal cell types; the ventr...
Neural Development 2015 10:24
Published on: 24 October 2015
Research article
In the visual system of most binocular vertebrates, the axons of retinal ganglion cells (RGCs) diverge at the diencephalic midline and extend to targets on both ipsi- and contralateral sides of the brain. Whil...
Neural Development 2015 10:23
Published on: 22 October 2015
Erratum
Neural Development 2015 10:22
Published on: 2 October 2015
The original article was published in Neural Development 2012 7:212
Research article
Rac1 is a critical regulator of cytoskeletal dynamics in multiple cell types. In the nervous system, it has been implicated in the control of cell proliferation, neuronal migration, and axon development.
Neural Development 2015 10:21
Published on: 23 September 2015
Short report
N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptors and are expressed throughout the central nervous system (CNS). Their activity is required for excitatory synaptic transmi...
Neural Development 2015 10:20
Published on: 17 September 2015
Research article
The dorsal lateral geniculate nucleus (dLGN) of the mouse has been an important experimental model for understanding thalamic circuit development. The developmental remodeling of retinal projections has been t...
Neural Development 2015 10:19
Published on: 15 July 2015
Research article
Nonsense mediated mRNA decay (NMD) is an RNA surveillance mechanism that controls RNA stability and ensures the speedy degradation of erroneous and unnecessary transcripts. This mechanism depends on several co...
Neural Development 2015 10:18
Published on: 21 June 2015
Research article
Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate circadian light entrainment and the pupillary light response in adult mice. In early development these cells mediate different processes, in...
Neural Development 2015 10:17
Published on: 21 June 2015
Erratum
Neural Development 2015 10:16
Published on: 19 June 2015
The original article was published in Neural Development 2015 10:3
