Table 1 Top 20 GO categories enriched among m6A targets, ranked by p-value. Count is the number of m6A targets in that category. Enrichment is the observed frequency of targets in that category (count / 867 total m6A targets) divided by the expected frequency (all genes in that category / total Drosophila genes)
GO Term | Definition | P value | Count | Enrichment |
|---|---|---|---|---|
GO:0022008 | neurogenesis | 2.0 × 10–112 | 233 | 5.5 |
GO:0007154 | cell communication | 1.2 × 10–92 | 291 | 3.6 |
GO:0048812 | neuron projection morphogenesis | 1.0 × 10–60 | 125 | 6.1 |
GO:0006355 | regulation of transcription | 1.2 × 10–46 | 171 | 3.5 |
GO:0007611 | learning or memory | 3.1 × 10–16 | 41 | 5.5 |
GO:0,050,808 | synapse organization | 4.1 × 10–15 | 54 | 4.0 |
GO:0016358 | dendrite development | 4.9 × 10–14 | 41 | 4.9 |
GO:0008219 | cell death | 6.0 × 10–13 | 59 | 3.3 |
GO:0007010 | cytoskeleton organization | 6.5 × 10–13 | 79 | 2.7 |
GO:0042063 | gliogenesis | 9.8 × 10–13 | 28 | 6.7 |
GO:0008039 | synaptic target recognition | 1.4 × 10–11 | 20 | 9.3 |
GO:0008356 | asymmetric cell division | 2.7 × 10–11 | 28 | 6.0 |
GO:0007405 | neuroblast proliferation | 8.0 × 10–11 | 26 | 6.2 |
GO:0016055 | Wnt signaling pathway | 1.6 × 10–10 | 30 | 5.2 |
GO:0050795 | regulation of behavior | 1.5 × 10–09 | 26 | 5.5 |
GO:0007268 | chemical synaptic transmission | 1.1 × 10–08 | 45 | 3.2 |
GO:0030509 | BMP signaling pathway | 1.3 × 10–07 | 18 | 6.9 |
GO:0048665 | neuron fate specification | 2.6 × 10–07 | 13 | 10.1 |
GO:0000165 | MAPK cascade | 3.6 × 10–06 | 26 | 4.0 |
GO:0055057 | neuroblast division | 6.4 × 10–05 | 13 | 6.9 |