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Fig. 3 | Neural Development

Fig. 3

From: Early development of the cochlea of the common marmoset, a non-human primate model

Fig. 3

Sensory epithelium specifications of the cochlea of the common marmoset. (A) In E70, CDKN1B and JAG1 expressions were not observed on the floor of the cochlear duct. (B and C) In E77, CDKN1B expression was detected in the floor of the elongating cochlear duct and in the apical turns (asterisk in B). At this stage, no JAG1 expression was detected in the cochlear duct. In the apical turn, CDKN1B expression was observed in a part of the SOX2-positive regions (C). (D) In E87, JAG1 expression was observed in the cochlea. (E–G) In E92, both CDKN1B and JAG1 expression was observed in the cochlea. JAG1 expression was observed in the medial side of the SOX2-positive region in the apical turn (Arrow in E). In contrast, JAG1 expression was detected more laterally and broadly in the basal turn (Arrow in F and G). The nuclei were counterstained with Hoechst (blue). Scale bar: 50 µm. OC: organ of Corti

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