Table 2 RGC subtype frequencies in different experimental ages and groups (relative to the total number of RGCs in an experimental group)
RGC subtype | ROSA Brn3aHET | ROSA Brn3aWT | E15 Brn3aHET | E15 Brn3aKO | P0 Brn3aHET | P0 Brn3aKO | P22 Brn3aHET | P22 Brn3aKO |
|---|---|---|---|---|---|---|---|---|
ON alpha | 8.9 | 6.5 | 7.4 | 9.5 | none | none | none | none |
M5 | 17.2 | 19.6 | 24.1 | 22.8 | none | none | none | none |
ON spiny | 1.2 | 0.7 | 2.8 | 0.9 | 2.2 | none | 4.7 | 8.3 |
ON and OFF β | 12.4 | 13.8 | 24.4 | 6.5 | 27 | 4.5 | 27 | 17.2 |
OFF transient | none | none | 0.6 | none | 3.4 | 9 | 2.7 | 2.8 |
OFF sustained | none | none | 0.6 | 0.9 | 1.1 | none | none | none |
M1 | none | 1.4 | none | none | none | none | none | none |
Brn3aKO β | none | none | none | none | none | 4.5 | none | 2.8 |
Mono Total | 39.6 | 42 | 59.9 | 40.5 | 34.8 | 18 | 35.8 | 31.7 |
ON–OFF DS | 37.3 | 34.8 | 12.7 | 23.3 | 19.1 | 39.3 | 31.8 | 35.8 |
SB | 15.4 | 12.3 | none | none | 28.1 | 21.3 | 22.3 | 20 |
Recursive | 1.2 | 5.1 | 11.4 | 21.1 | 18 | 14.6 | 9.5 | 7.6 |
Large Bistratified | 2.4 | none | none | none | none | 3.4 | 0.7 | 4.8 |
ON DS | 3.6 | 5.8 | 4 | 3.4 | none | none | none | none |
Abnormal type 1 | none | none | 7.7 | 8.2 | none | none | none | none |
Abnormal type 2 | none | none | 4.3 | 3.4 | none | none | none | none |
Brn3aKO Bistr | none | none | none | none | none | 3.4 | none | none |
Bi Total | 60.4 | 58 | 40.1 | 59.5 | 65.2 | 82 | 64.2 | 68.3 |