Fig. 1
From: The role of astrocyte‐mediated plasticity in neural circuit development and function
Astrocytes locally support neuronal synapses.
a Light microscopy image of single astrocyte (cyan) contacting the pre-synaptic membrane of the Drosophila A18b neuron (magenta), with pre-synapses highlighted in the inset (yellow). First instar larva. Genotype: A18b (94E10-lexA; 8xlexAop-2xBrp-short::cherry; lexAop-myr::GFP), astrocyte (25h07-gal4; hs-FLPG5;; 10xUAS(FRT.stop)myr::smGdP-HA, 10xUAS(FRT.stop)myr::smGdP-V5, 10xUAS-(FRT.stop)myr::smGdP-FLAG). Scale bar, 200 nm.
b TEM image showing a single astrocyte (cyan) contacting the pre-synaptic membrane of the A18b neuron (magenta), and the post-synaptic membrane of an A27a neuron (green) with synapses highlighted (yellow asterisks). Genotype: wild type. First instar larva. Scale bar, 500 nm