Skip to main content
Fig. 7 | Neural Development

Fig. 7

From: A novel temporal identity window generates alternating Eve+/Nkx6+ motor neuron subtypes in a single progenitor lineage

Fig. 7

Nkx6 is necessary and sufficient to specify VO motor neuron axon targeting to ventral oblique muscles. a In controls (NB7–1-gal4 UAS-myr:GFP), NB7–1 progeny project to the ventral oblique muscles. b Nkx6 overexpression (NB7–1-gal4 UAS-myr:GFP UAS-Nkx6) leads to ectopic projections to ventral oblique muscles. Scale bar: 10 μm. c MCFO labeling of single motor neurons in the NB7–1 lineage shows two different HA+ and V5+ motor neurons projecting via the ISNd to the ventral oblique muscles. Scale bar: 7 μm. d Quantification. e Summary. f Reducing Nkx6 levels (NB7–1-gal4 UAS-myr:GFP UAS-Nkx6-RNAi) decreases projections out the ISNd to the ventral oblique muscles

Back to article page

Neural Development

ISSN: 1749-8104