Fig. 5

Abl 1Q is required to regulate Ena at the midline. a-h Late-stage embryonic nerve cords stained with mAb 1D4. a Wild-type embryo. bAbl homozygotes show occasional midline crossing overs, rescued by expression of c wild-type Abl with elav-Gal4. d Expression of AblΔ1Q with elav-Gal4 further increases crossing over. e Midline crossing overs are partially rescued by heterozygosity of ena.f With ena heterozygosity, AblΔ1Q still shows many midline crossing overs. g Overexpression of ena further increase crossing overs, and h expression of ena behaves synergistically with AblΔ1Q to cause numerous defects. i Quantification of crossing overs in Abl mutants expressing Abl transgenes with elav-Gal4, with heterozygous loss or overexpression of ena. Confidence intervals given are for penetrance of the phenotype. All counts are from 3 or more sets of embryo collections, with ~ 30 embryos per set; the n-value represents embryo count. Confidence intervals given are for penetrance of the phenotype