Fig. 3

The 1Q region of Abl is required for Abi and Trio genes to modify ISNb stop shorts in Abl loss-of-function mutant embryos. a The ISNb innervates the clefts between muscles 6/7, 6/13 and 12/13. In Abl mutants, the ISNb occasionally fails to innervate the 12/13 cleft (6/13 stop short) or 6/12 cleft (6/7 stop short). b Wild-type ISNb innervations. dAbl mutant showing ISNb stop shorts (black arrow indicates 12/13 cleft). Expressing either dAblΔ1Q or eena increases stop shorts in Abl mutants. f Expression of both does not further increase stop shorts but causes variable misrouting or fasciculation defects in motoneuron projections (white arrows). g Stop short counts in Abl mutants expressing Abl transgenes, with overexpression of Abi or trio with 1407-Gal4. h Stop short counts with heterozygous loss and overexpression of ena with elav-Gal4. All counts are of individual hemisegments from 10 or more embryos, repeated over 3 or more sets of embryo collections; the n-value represents total hemisegments counted. Confidence intervals given are for penetrance of the phenotype