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Fig. 2 | Neural Development

Fig. 2

From: Microglia in the developing retina

Fig. 2

Spatiotemporal distribution of microglia in the developing mouse retina. a. Representative images showing distinct spatiotemporal localization patterns of microglia across retina development (E18, P3, P9, and P17) in CX3CR1GFP/+ mice. Microglia are highly enriched at E18 and P3 in the nascent IPL where synapses are developing. At P9, microglia also become present within the developing OPL. This pattern persists into adulthood. Blue, DAPI; green, microglia. Scale bar = 50 μm. b-c. Representative images (b, scale bar = 50 μm) and single cell reconstructions (c, scale bar = 10 μm) of microglia in whole mount preparations of CX3CR1GFP/+ retina across development (P0, P3, P9, and P20). At birth, retinal microglia are amoeboid but become progressively ramified as the retina matures

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