Table 2 Genetic and Molecular Tools for Identifying ipRGC subtypes (in adult animals)
Mouse Line/Antibody | Subtype Labeled | Other RGCs Labeled |
|---|---|---|
Opn4-GFP | M1-M3 | None |
Opn4 Cre/+ ;ZEG | M1-M6 | None |
Opn4 LacZ/+ | M1 | None |
SMI-32 | M4 (ON sustained alpha) | OFF sustained alpha and OFF transient alpha RGCs |
Anti-Brn3a | None | ~ 70% of conventional RGCs |