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Fig. 8 | Neural Development

Fig. 8

From: Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development

Fig. 8

Action potential properties of ipRGC subtypes across development. a Representative traces of single action potentials for M1, M2, and M4 subtypes for P6 and Adult timepoints. (B-D) Measurement of M1 ipRGC AP full width at half max (b), AP threshold (c), and AP AHP (d). AP AHP P6 for M1 subtype is not plotted because cells did not hyperpolarize after action potential elicitation. (E-G) Measurement of M2 ipRGC AP full width at half max (e), AP threshold (f), and AP AHP (g). h-j Measurement of M4 ipRGC AP full width at half max (h), AP threshold (i), and AP AHP (j). Graphs are Mean ± SD, n = 5–14 per subtype/age, *p < 0.05 when compared to Adult timepoint. AP: action potential, AHP: after hyperpolarization. Blue arrow indicates width at half-max, red dotted line indicates threshold, and black arrowhead indicates after hyperpolarization

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