TY - JOUR AU - Miterko, Lauren N. AU - White, Joshua J. AU - Lin, Tao AU - Brown, Amanda M. AU - O’Donovan, Kevin J. AU - Sillitoe, Roy V. PY - 2019 DA - 2019/03/12 TI - Persistent motor dysfunction despite homeostatic rescue of cerebellar morphogenesis in the Car8 waddles mutant mouse JO - Neural Development SP - 6 VL - 14 IS - 1 AB - Purkinje cells play a central role in establishing the cerebellar circuit. Accordingly, disrupting Purkinje cell development impairs cerebellar morphogenesis and motor function. In the Car8wdl mouse model of hereditary ataxia, severe motor deficits arise despite the cerebellum overcoming initial defects in size and morphology. SN - 1749-8104 UR - https://doi.org/10.1186/s13064-019-0130-4 DO - 10.1186/s13064-019-0130-4 ID - Miterko2019 ER -