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Fig. 3 | Neural Development

Fig. 3

From: Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors

Fig. 3

Hemispheres recover better than the vermis in Atoh1-Gli2 CKO mice. a-b Hemispheric sagittal sections of P30 Gli2lox/lox (control, a) and Atoh1-Cre/+; Gli2lox/lox (Atoh1-Gli2 CKO, b) cerebella stained with Hematoxilin/Eosin (H&E). c Graph of the area of hemispheric sagital sections of P30 Gli2lox/lox (control, black) (n = 6) and Atoh1-Cre/+; Gli2lox/lox (Atoh1-Gli2 CKO, red) (n = 6) CB. (d-i) Hemispheric sagittal sections of P4 (d-e), P8 (f-g) and P12 (h-i) Gli2lox/lox (control, d, f and h) and Atoh1-Cre/+; Gli2lox/lox (Atoh1-Gli2 CKO, e, g and i) cerebella stained with H&E. White arrow indicates the presence of extra folia. Scale bars represent 1 mm (a-b) and 500 μm (b-c and d-i)

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Neural Development

ISSN: 1749-8104