Fig. 2

The size of the cerebellum partially recovers in Atoh-Gli2 CKOs over time. a-c Mid-sagittal sections of P30 Gli2^lox/lox (control, a) and Atoh1-Cre/+; Gli2^lox/lox (Atoh1-Gli2 CKO, b-c) cerebella stained with Hematoxilin and Eosin (H&E). d Graph of the area of mid-sagital CB sections of P30 Gli2^lox/lox (control, black) (n = 6) and Atoh1-Cre/+; Gli2^lox/lox (Atoh1-Gli2 CKO, red) (n = 6) mice. e-j Mid-sagittal CB sections of P4 (e-f), P8 (g-h) and P12 (i-j) Gli2^lox/lox (control, e, g and i) and Atoh1-Cre/+; Gli2^lox/lox (Atoh1-Gli2 CKO, f, h and j) mice stained with H&E. k Graph of the area of 3 mid-sagital sections of Gli2^lox/lox (control, P0: n = 3, P4: n = 3, P8: n = 3, P12: n = 3 and P30: n = 6) and Atoh1-Cre/+; Gli2^lox/lox (Atoh1-Gli2 CKO, P0: n = 3, P4: n = 3, P8: n = 6, P12: n = 4 and P30: n = 6) cerebella. l Graph showing the decrease in area of 3 mid-sagital sections of Atoh1-Gli2 CKO cerebella as a percentage of controls during development. All graphical data are presented as means ± SEM and significance determined using two-tailed T-test. Scale bars represent 1 mm