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Fig. 2 | Neural Development

Fig. 2

From: The absence of retinal input disrupts the development of cholinergic brainstem projections in the mouse dorsal lateral geniculate nucleus

Fig. 2

Relationship between cholinergic projections and the optic tract (OT). Coronal sections depicting OT (labeled with CTB-AF-488, green), cholinergic axons (labeled with tdT, red), and a merged image at the level of dLGN (A), cerebral peduncle (B), and optic chiasm (C). a Cholinergic axons course within OT along the dorsolateral border of dLGN. Dotted line delineates the border between the OT and dLGN. Scale bar = 30 μm. b Cholinergic axons travel within the supraoptic decussation (SOX) along the lateral edge of the cerebral peduncle (CP). Lateral to SOX, cholinergic axons also are seen coursing through OT. Dotted line delineates the border between SOX and OT. Scale bar = 30 μm. c Cholinergic axons are found along midline in SOX, just below the optic chiasm (OX) and also laterally in OT. Scale bar = 200 μm. In panels A-C, arrows depict location of cholinergic axons within OT

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Neural Development

ISSN: 1749-8104