Fig. 4

OCT and SOX motifs required for hs623 activity in primary MGE cultures. a Schematic of hs623 with LHX6, OCT and SOX motifs. b Luciferase reporter assay showing a reduced activity of hs623 when LHX6, OCT and SOX motifs in hs623 are mutated. Data are represented as mean ± SEM. Unpaired t-test was used to test significance between the groups: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001