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Fig. 5 | Neural Development

Fig. 5

From: FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord

Fig. 5

Inactivation of FGFRs does not affect cell survival and proliferation of spinal cord cells. a-b Detection of clived Caspase 3 (green) and Nkx2.2 (red) on transverse sections of spinal cord explants cultivated in control condition (a) or in presence of SU5402 (b). c-d Detection of BrdU (green) and Olig2 (red in c and d, c', d') in control condition (c, c') or in presence of SU5402 (d, d'). BrdU pulse has been performed at 32 h after plating. e Quantification of BrdU-positive cells and Caspase 3-positive cells in the p3 (Olig2-negative) and pMN (Olig2-positive) domains of the progenitor zone on explants cultivated in control condition or in presence of SU5402. Scale bars = 50 μm

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