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Fig. 7 | Neural Development

Fig. 7

From: Fate bias during neural regeneration adjusts dynamically without recapitulating developmental fate progression

Fig. 7

Following genetic ablation, new horizontal and amacrine cells can be observed prior to the proliferative wave. a-c) Micrographs of retinal sections in Tg(ptf1a:GFP) larvae at different days post injury (dpi). d Quantification shows an initial reduction and subsequent increase in the number of Ptf1a:GFP labelled inhibitory neurons. At 3 and 4 dpi, the number is significantly lower (* p-value = 0.018, ** p-value ≤0.01) compared to 1 dpi (baseline) or 5 dpi (regenerated), which are not significantly different from each other (p-value = 0.50). Ns: not significant (p-value >0.05). Results are mean ± SEM. INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer. Scale bar C = 50 μm

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Neural Development

ISSN: 1749-8104