Skip to main content
Fig. 5. | Neural Development

Fig. 5.

From: Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord

Fig. 5.

Efnb2 interacts with Shh to control the ratio between pMN and p3 progenitors. a, b. Transverse sections of Efnb2 lox/GFP (a) and Efnb2 lox/GFP ;Olig2-Cre (b) E11.5 embryos were immunostained to detect Olig2 (red) and Nkx2.2 (blue). c. The number of Olig2+, Nkx2.2+ and Olig2+/ Nkx2.2+ (double) progenitors was quantified (n=5 embryos per genotype). Total refers to the sum of Olig2+ and Nkx2.2+ progenitors. Error bars indicate s.e.m.; **P<0.01 ns= non significant (Mann-Whitney-Wilcoxon test). d-g. Transverse sections of E11.5 embryos of different genotypes (as indicated) were immunostained for Olig2 (red) and Nkx2.2 (blue). h. Quantification of the number of Olig2+, Nkx2.2+ and Olig2+/ Nkx2.2+ (double) progenitors was quantified for each genotype (n=5 embryos per genotype). Total refers to the sum of Olig2+ and Nkx2.2+ progenitors. Error bars indicate s.e.m.; *P<0.05; **P<0.01; (Mann-Whitney-Wilcoxon test). Scale bars: 50 μm.

Back to article page
\