Fig. 2

Spatial- and temporal-specific patterns of OSN neurogenesis in the OE. a In situ hybridization of OE sections from a P7 mouse using probes for OR genes (M72, P2, I7, and MOR28). The OE was subdivided into four zones based on OR gene expression patterns. The zones defined by the ORs are indicated by dashed lines. Note that the M72-area corresponds to the D-zone of the OE. b Proportions of EdU-labeled OSNs within the OR-defined zones. EdU injection was performed at E13.5, 15.5, 17.5, and P0, and distribution patterns were analyzed at P7. c Quantification of proliferation levels, defined as the density of EdU-labeled OSNs within OR-defined zones. n = 3 sections from 3 animals, error bars indicate SEM. Scale bar, 100 μm