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Fig. 7 | Neural Development

Fig. 7

From: Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain

Fig. 7

Loss of Ascl1 led to very specific downregulation of Tagln3 and Chga. Expression of Tagln3 in control (a, n = 3) and Ascl1 null mutant embryos (b, n = 3). Expression was lost specifically in the locus coeruleus (LC; unfilled arrowhead). (c, d) Whole mount embryos. Expression of Chga in control (c, n = 3) and Ascl1 null mutant embryos (d, n = 2). Expression was specifically lost in the nTPC (filled arrowhead), LC and cda. (c’, d’) Inserts indicate Chga expression in flatmounted brains in lateral view of the embryos in c and d. For abbreviations see Table 1. gV: trigeminal ganglion; gVII/VIII: facial and vestibulocochlear ganglia; gIX: petrosal ganglion; gX: nodose ganglion

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Neural Development

ISSN: 1749-8104