Fig. 7From: Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brainLoss of Ascl1 led to very specific downregulation of Tagln3 and Chga. Expression of Tagln3 in control (a, n = 3) and Ascl1 null mutant embryos (b, n = 3). Expression was lost specifically in the locus coeruleus (LC; unfilled arrowhead). (c, d) Whole mount embryos. Expression of Chga in control (c, n = 3) and Ascl1 null mutant embryos (d, n = 2). Expression was specifically lost in the nTPC (filled arrowhead), LC and cda. (c’, d’) Inserts indicate Chga expression in flatmounted brains in lateral view of the embryos in c and d. For abbreviations see Table 1. gV: trigeminal ganglion; gVII/VIII: facial and vestibulocochlear ganglia; gIX: petrosal ganglion; gX: nodose ganglionBack to article page