Skip to main content
Fig. 7 | Neural Development

Fig. 7

From: Oligodendrocyte development in the embryonic tuberal hypothalamus and the influence of Ascl1

Fig. 7

Mid- to late- embryonic Sox9+, Olig2+, Sox10+ glial populations in the tuberal hypothalamus of Control, Neurog2 GFPKI/GFPKI and Ascl1 GFPKI/GFPKI mutant embryo brains. Example images of (a) Sox9+, c Olig2+ glial precursors at E15.5 and E17.5. Total number of (b) Sox9+ and d Olig2+ glioblasts counted in the mantle region in control, Neurog2 GFPKI/GFPKI and Ascl1 GFPKI/GFPKI embryo brains. e Olig2/Sox10, Olig2/Aldh1L1 and cleaved Caspase3/GFP immunolabeled E17.5 control and Ascl1 GFPKI/GFPKI mutant embryo brains. Total number of (f) Sox10+ OPCs and g Aldh1L1+ astrocytes counted in control and Ascl1 GFPKI/GFPKI embryo brains. h Sox10 and Sox10/Olig2 immunolabeled E17.5 control and Ascl1 GFPKI/GFPKI mutant embryo brains. 3 V outlined with solid white line, hypothalamic sulcus indicated with dotted white line. Bar graphs represent mean ± SD (n = 3 embryos per group; 2 brain sections per embryo). Statistics: *P < 0.01, **P < 0.001, ***P < 0.0001. ANOVA with Tukey Post-Hoc or Student’s t-test

Back to article page