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Fig. 7 | Neural Development

Fig. 7

From: Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development

Fig. 7

mir-135a-2OE in mice heterozygous for endogenous mir-135a-2. a-b ish showing Lmx1a expression in E12.5 control (Emx1::Cre;mir-135a-2 +/-) (a) and mutant (Emx1::Cre;mir-135a-2OE;mir-135a-2 +/-) (b) brains. Dashed lines highlight the cortical hem area and the neocortical domain size. c Quantification of the cortical hem area (μm2 ± SEM) along the rostro-caudal axis (n = 3). d Quantification of the neocortex length (μm ± SEM) from the PSB to the hem at the same levels (n = 3). ch, cortical hem; cp, choroid plexus; PSB, pallium-subpallium boundary; ncx, neocortex. Scale bar 100 μm in panels a and b

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